Role of total artificial heart in the management of heart transplant rejection and retransplantation: Case report and review

Anantharam Kalya; Dawn Jaroszewski; Octavio Pajaro; Robert Scott; Radha Gopalan; Diane Kasper; Francisco Arabia

doi:10.1111/ctr.12146

Role of total artificial heart in the management of heart transplant rejection and retransplantation: Case report and review

Anantharam Kalya, Dawn Jaroszewski, Octavio Pajaro, Robert Scott, Radha Gopalan, Diane Kasper, Francisco Arabia

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

Cardiac allograft rejection and failure may require mechanical circulatory support as bridge-to-retransplantation. Prognosis in this patient group is poor and implantable ventricular assist devices have had limited success due to organ failure associated with the high dose immunosuppression required to treat ongoing rejection. We present a case from our institution and the world-wide experience utilizing the SynCardia CardioWest Total Artificial Heart (TAH-t; SynCardia Systems, Inc., Tucson, AZ, USA) for replacement of the failing graft, recovery of patient and end-organ failure with ultimate bridge to retransplantation. We present our experience and review of world-wide experience for use of TAH-t in this type patient.

Original language	English (US)
Pages (from-to)	E348-E350
Journal	Clinical Transplantation
Volume	27
Issue number	4
DOIs	https://doi.org/10.1111/ctr.12146
State	Published - Jul 2013

Keywords

Cardiac rejection
Heart transplant
Immunosuppression
Retransplantation
Total artificial heart

ASJC Scopus subject areas

Transplantation

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10.1111/ctr.12146

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title = "Role of total artificial heart in the management of heart transplant rejection and retransplantation: Case report and review",

abstract = "Cardiac allograft rejection and failure may require mechanical circulatory support as bridge-to-retransplantation. Prognosis in this patient group is poor and implantable ventricular assist devices have had limited success due to organ failure associated with the high dose immunosuppression required to treat ongoing rejection. We present a case from our institution and the world-wide experience utilizing the SynCardia CardioWest Total Artificial Heart (TAH-t; SynCardia Systems, Inc., Tucson, AZ, USA) for replacement of the failing graft, recovery of patient and end-organ failure with ultimate bridge to retransplantation. We present our experience and review of world-wide experience for use of TAH-t in this type patient.",

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AU - Kalya, Anantharam

AU - Jaroszewski, Dawn

AU - Pajaro, Octavio

AU - Scott, Robert

AU - Gopalan, Radha

AU - Kasper, Diane

AU - Arabia, Francisco

PY - 2013/7

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AB - Cardiac allograft rejection and failure may require mechanical circulatory support as bridge-to-retransplantation. Prognosis in this patient group is poor and implantable ventricular assist devices have had limited success due to organ failure associated with the high dose immunosuppression required to treat ongoing rejection. We present a case from our institution and the world-wide experience utilizing the SynCardia CardioWest Total Artificial Heart (TAH-t; SynCardia Systems, Inc., Tucson, AZ, USA) for replacement of the failing graft, recovery of patient and end-organ failure with ultimate bridge to retransplantation. We present our experience and review of world-wide experience for use of TAH-t in this type patient.

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Role of total artificial heart in the management of heart transplant rejection and retransplantation: Case report and review

Abstract

Keywords

ASJC Scopus subject areas

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