Role of total artificial heart in the management of heart transplant rejection and retransplantation: Case report and review

Anantharam Kalya, Dawn Jaroszewski, Octavio Pajaro, Robert Scott, Radha Gopalan, Diane Kasper, Francisco Arabia

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Cardiac allograft rejection and failure may require mechanical circulatory support as bridge-to-retransplantation. Prognosis in this patient group is poor and implantable ventricular assist devices have had limited success due to organ failure associated with the high dose immunosuppression required to treat ongoing rejection. We present a case from our institution and the world-wide experience utilizing the SynCardia CardioWest Total Artificial Heart (TAH-t; SynCardia Systems, Inc., Tucson, AZ, USA) for replacement of the failing graft, recovery of patient and end-organ failure with ultimate bridge to retransplantation. We present our experience and review of world-wide experience for use of TAH-t in this type patient.

Original languageEnglish (US)
Pages (from-to)E348-E350
JournalClinical Transplantation
Volume27
Issue number4
DOIs
StatePublished - Jul 1 2013

Keywords

  • Cardiac rejection
  • Heart transplant
  • Immunosuppression
  • Retransplantation
  • Total artificial heart

ASJC Scopus subject areas

  • Transplantation

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