Role of thyrotropin measurements in the diagnosis and management of thyroid disease

G. G. Klee, I. D. Hay

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

This article reviews the role of thyrotropin assays in clinical medicine and illustrates the advantages and limitations of assays that can measure subnormal concentrations. Analytic considerations that can significantly alter the performance of these assays are outlined. The concept of assay generations is defined, and the potential roles of third and fourth generation assays are postulated. In addition, a diagnostic strategy is presented for using TSH and other procedures in the diagnosis and management of thyroid disease.

Original languageEnglish (US)
Pages (from-to)673-682
Number of pages10
JournalClinics in Laboratory Medicine
Volume13
Issue number3
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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