Role of thyrotropin measurements in the diagnosis and management of thyroid disease

G. G. Klee, Ian D Hay

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

This article reviews the role of thyrotropin assays in clinical medicine and illustrates the advantages and limitations of assays that can measure subnormal concentrations. Analytic considerations that can significantly alter the performance of these assays are outlined. The concept of assay generations is defined, and the potential roles of third and fourth generation assays are postulated. In addition, a diagnostic strategy is presented for using TSH and other procedures in the diagnosis and management of thyroid disease.

Original languageEnglish (US)
Pages (from-to)673-682
Number of pages10
JournalClinics in Laboratory Medicine
Volume13
Issue number3
StatePublished - 1993

Fingerprint

Clinical Medicine
Thyroid Diseases
Thyrotropin
Assays
Medicine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Role of thyrotropin measurements in the diagnosis and management of thyroid disease. / Klee, G. G.; Hay, Ian D.

In: Clinics in Laboratory Medicine, Vol. 13, No. 3, 1993, p. 673-682.

Research output: Contribution to journalArticle

@article{bf367f36f39b42f2ba69660903ad7af5,
title = "Role of thyrotropin measurements in the diagnosis and management of thyroid disease",
abstract = "This article reviews the role of thyrotropin assays in clinical medicine and illustrates the advantages and limitations of assays that can measure subnormal concentrations. Analytic considerations that can significantly alter the performance of these assays are outlined. The concept of assay generations is defined, and the potential roles of third and fourth generation assays are postulated. In addition, a diagnostic strategy is presented for using TSH and other procedures in the diagnosis and management of thyroid disease.",
author = "Klee, {G. G.} and Hay, {Ian D}",
year = "1993",
language = "English (US)",
volume = "13",
pages = "673--682",
journal = "Clinics in Laboratory Medicine",
issn = "0272-2712",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Role of thyrotropin measurements in the diagnosis and management of thyroid disease

AU - Klee, G. G.

AU - Hay, Ian D

PY - 1993

Y1 - 1993

N2 - This article reviews the role of thyrotropin assays in clinical medicine and illustrates the advantages and limitations of assays that can measure subnormal concentrations. Analytic considerations that can significantly alter the performance of these assays are outlined. The concept of assay generations is defined, and the potential roles of third and fourth generation assays are postulated. In addition, a diagnostic strategy is presented for using TSH and other procedures in the diagnosis and management of thyroid disease.

AB - This article reviews the role of thyrotropin assays in clinical medicine and illustrates the advantages and limitations of assays that can measure subnormal concentrations. Analytic considerations that can significantly alter the performance of these assays are outlined. The concept of assay generations is defined, and the potential roles of third and fourth generation assays are postulated. In addition, a diagnostic strategy is presented for using TSH and other procedures in the diagnosis and management of thyroid disease.

UR - http://www.scopus.com/inward/record.url?scp=0027313575&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027313575&partnerID=8YFLogxK

M3 - Article

VL - 13

SP - 673

EP - 682

JO - Clinics in Laboratory Medicine

JF - Clinics in Laboratory Medicine

SN - 0272-2712

IS - 3

ER -