Role of structural MRI in Alzheimer's disease

Research output: Contribution to journalReview article

48 Scopus citations


Atrophy measured on structural magnetic resonance imaging (sMRI) is a powerful biomarker of the stage and intensity of the neurodegenerative aspect of Alzheimer's disease (AD) pathology. In this review, we will discuss the role of sMRI as an AD biomarker by summarizing (a) the most commonly used methods to extract information from sMRI images, (b) the different roles in which sMRI can be used as an AD biomarker, and (c) comparisons of sMRI with other major AD biomarkers.

Original languageEnglish (US)
Article number23
JournalAlzheimer's Research and Therapy
Issue number4
StatePublished - Sep 10 2010


ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Cognitive Neuroscience

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