Role of PAPP-A in aging and age-related disease

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

As suggested by its name, pregnancy-associated plasma protein-A (PAPP-A) plays an important role in pregnancy and fetal development (Brizot et al., 1996; Lin et al., 1974; Smith et al., 2002). On the opposite end of life's spectrum, recent studies using genetically-engineered mice indicate a newly recognized role for PAPP-A in aging and in the development of age-related disease. These latter studies will be reviewed in this article.

Original languageEnglish (US)
Pages (from-to)612-613
Number of pages2
JournalExperimental Gerontology
Volume48
Issue number7
DOIs
StatePublished - Jul 2013

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Pregnancy-Associated Plasma Protein-A
Aging of materials
Fetal Development
Names
Pregnancy

Keywords

  • Aging
  • Atherosclerosis
  • Cancer
  • Insulin-like growth factors
  • Pregnancy-associated plasma protein-A

ASJC Scopus subject areas

  • Aging
  • Biochemistry
  • Cell Biology
  • Endocrinology
  • Genetics
  • Molecular Biology

Cite this

Role of PAPP-A in aging and age-related disease. / Conover, Cheryl A.

In: Experimental Gerontology, Vol. 48, No. 7, 07.2013, p. 612-613.

Research output: Contribution to journalArticle

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