Role of Mass Spectrometry in Clinical Endocrinology

Siva S. Ketha, Ravinder Jit Singh, Hemamalini Ketha

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The advent of mass spectrometry into the clinical laboratory has led to an improvement in clinical management of several endocrine diseases. Liquid chromatography tandem mass spectrometry found some of its first clinical applications in the diagnosis of in-born errors of metabolism, quantitative steroid analysis, and in-drug analysis laboratories. Mass spectrometry assays offer analytical sensitivity and specificity that is superior to immunoassays for many analytes. This review highlights several areas of clinical endocrinology that have witnessed the use of liquid chromatography tandem mass spectrometry to improve clinical outcomes.

Original languageEnglish (US)
JournalEndocrinology and Metabolism Clinics of North America
DOIs
StateAccepted/In press - 2017

Keywords

  • IGF1 by mass spectrometry
  • Liquid chromatography mass spectrometry in clinical endocrinology
  • Liquid chromatography tandem mass spectrometry
  • Steroid Liquid chromatography tandem mass spectrometry

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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