Role of amiodarone in the treatment of fetal supraventricular tachyarrhythmias and hydrops fetalis

A. Khositseth, K. D. Ramin, P. W. O'Leary, C. J. Porter

Research output: Contribution to journalArticle

14 Scopus citations


We report three consecutive hydropic fetuses with fetal tachyarrhythmias treated with amiodarone - two in combination with digoxin and one with digoxin, procainamide, and propranolol. Sinus rhythm was achieved in one case and ventricular rate control was achieved in two cases. All fetuses treated with amiodarone gradually improved. Observed side effects of amiodarone were a maternal rash in one mother and transient neonatal hypothyroidism in one infant. We conclude that amiodarone might be effective and safe for fetal tachyarrhythmias and impending hydrops. The small number of patients suggests that a multicenter cooperative approach is required in order to determine if this is correct.

Original languageEnglish (US)
Pages (from-to)454-456
Number of pages3
JournalPediatric Cardiology
Issue number5
StatePublished - Sep 2003



  • Amiodarone
  • Fetal supraventricular tachyarrhythmias
  • Hydrops fetalis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pediatrics, Perinatology, and Child Health

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