Role and future of MRi in radiation oncology

Indra J. Das, Kiaran Patrick McGee, Neelam Tyagi, Hesheng Wang

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Technical innovations and developments in areas such as disease localization, dose calculation algorithms, motion management and dose delivery technologies have revolutionized radiation therapy resulting in improved patient care with superior outcomes. A consequence of the ability to design and accurately deliver complex radiation fields is the need for improved target visualization through imaging. While CT imaging has been the standard of care for more than three decades, the superior soft tissue contrast afforded by MR has resulted in the adoption of this technology in radiation therapy. With the development of real time MR imaging techniques, the problem of real time motion management is enticing. Currently, the integration of an MR imaging and megavoltage radiation therapy treatment delivery system (MR-linac or MRL) is a reality that has the potential to provide improved target localization and real time motion management during treatment. Higher magnetic field strengths provide improved image quality potentially providing the backbone for future work related to image texture analysis—a field known as Radiomics—thereby providing meaningful information on the selection of future patients for radiation dose escalation, motion-managed treatment techniques and ultimately better patient care. On-going advances in MRL technologies promise improved real time soft tissue visualization, treatment margin reductions, beam optimization, inhomogeneity corrected dose calculation, fast multileaf collimators and volumetric arc radiation therapy. This review article provides rationale, advantages and disadvantages as well as ideas for future research in MRI related to radiation therapy mainly in adoption of MRL.

Original languageEnglish (US)
Article number20180505
JournalBritish Journal of Radiology
Volume92
Issue number1094
DOIs
StatePublished - Jan 1 2019

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Radiation Oncology
Radiotherapy
Time Management
Technology
Patient Care
Radiation
Aptitude
Magnetic Fields
Therapeutics
Standard of Care
Patient Selection

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Role and future of MRi in radiation oncology. / Das, Indra J.; McGee, Kiaran Patrick; Tyagi, Neelam; Wang, Hesheng.

In: British Journal of Radiology, Vol. 92, No. 1094, 20180505, 01.01.2019.

Research output: Contribution to journalReview article

Das, Indra J. ; McGee, Kiaran Patrick ; Tyagi, Neelam ; Wang, Hesheng. / Role and future of MRi in radiation oncology. In: British Journal of Radiology. 2019 ; Vol. 92, No. 1094.
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