@inproceedings{9166bc35d90f4156bdb2072881f1d743,
title = "Robust 3-D reconstruction and analysis of microstructures from serial histologic sections, with emphasis on microvessels in prostate cancer",
abstract = "We have developed a technique to reconstruct 3-D microstructures from serial histologic section, and demonstrated the robustness of the method on microvessels associated with prostate cancer and bile ducts in liver specimens. The method is critically based on image coregistration techniques, particularly two dimensional surface matching between extracted image features. The reconstruction paradigm allows 3-D regions of information in several locations throughout a block of tissue to be obtained at different magnifications while maintaining proper spatial relationship to the original data. The reconstructed objects have a generally unmapped and unknown topography. Visualizing anatomic microstructures in 3-D and analyzing their topography will help physicians to better understand and correctly interpret changes in disease.",
author = "Kay, {Paul A.} and Robb, {Richard A.} and Bostwick, {David G.} and Camp, {Jon J.}",
note = "Publisher Copyright: {\textcopyright} Springer-Verlag Berlin Heidelberg 1996.; 4th International Conference on Visualization in Biomedical Computing, VBC 1996 ; Conference date: 22-09-1996 Through 25-09-1996",
year = "1996",
doi = "10.1007/bfb0046946",
language = "English (US)",
isbn = "3540616497",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "129--134",
editor = "Hohne, {Karl Heinz} and Ron Kikinis",
booktitle = "Visualization in Biomedical Computing - 4th International Conference, VBC 1996, Proceedings",
}