TY - JOUR
T1 - Risks for renal dysfunction with cardiac angiography
AU - Taliercio, C. P.
AU - Vlietstra, R. E.
AU - Fisher, L. D.
AU - Burnett, J. C.
PY - 1986
Y1 - 1986
N2 - In 139 patients with preexisting abnormal renal function (serum creatinine level of 2.0 mg/dL or greater) undergoing cardiac angiography (141 examinations), the incidence of contrast nephropathy, defined as 1 mg/dL or greater rise in serum creatinine, was 23% (95% confidence interval, 17% to 30%). Stepwise logistic regression analysis showed that contrast nephropathy was independently associated with class IV heart failure with low cardiac output (71% incidence in this subgroup; p<0.0001), multiple radiocontrast studies within 72 hours (50%; p=0.002), dose of radiocontrast administered (p=0.009), and insulin-dependent diabetes mellitus (44%; p=0.007). Age, hypertension, and hyperuricemia were not associated. In patients without low cardiac output, other radiocontrast tests, or insulin-dependent diabetes mellitus, there was a 2% incidence of contrast nephropathy in those who received less than 125 mL radiocontrast and a 19% incidence in those who received 125 mL or greater.
AB - In 139 patients with preexisting abnormal renal function (serum creatinine level of 2.0 mg/dL or greater) undergoing cardiac angiography (141 examinations), the incidence of contrast nephropathy, defined as 1 mg/dL or greater rise in serum creatinine, was 23% (95% confidence interval, 17% to 30%). Stepwise logistic regression analysis showed that contrast nephropathy was independently associated with class IV heart failure with low cardiac output (71% incidence in this subgroup; p<0.0001), multiple radiocontrast studies within 72 hours (50%; p=0.002), dose of radiocontrast administered (p=0.009), and insulin-dependent diabetes mellitus (44%; p=0.007). Age, hypertension, and hyperuricemia were not associated. In patients without low cardiac output, other radiocontrast tests, or insulin-dependent diabetes mellitus, there was a 2% incidence of contrast nephropathy in those who received less than 125 mL radiocontrast and a 19% incidence in those who received 125 mL or greater.
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U2 - 10.7326/0003-4819-104-4-501
DO - 10.7326/0003-4819-104-4-501
M3 - Article
C2 - 3954277
AN - SCOPUS:0022621983
SN - 0003-4819
VL - 104
SP - 501
EP - 504
JO - Annals of internal medicine
JF - Annals of internal medicine
IS - 4
ER -