Risk-reduction mastectomy: Clinical issues and research needs

Michael Stefanek, Lynn Hartmann, Wendy Nelson

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer. High-risk women, including women with a strong family history of breast cancer and BRCA1/2 mutation carriers, have several clinical options: risk-reduction surgery (bilateral mastectomy and bilateral oophorectomy), surveillance (mammography, clinical breast examination, and breast self-examination), and chemoprevention (tamoxifen). We review research in a number of areas central to our understanding of RRM, including recent data on 1) the effectiveness of RRM in reducing breast cancer risk, 2) the perception of RRM among women at increased risk and health-care providers, 3) the decision-making process for follow-up care of women at high risk, and 4) satisfaction and psychological status after surgery. We suggest areas of future research to better guide high-risk women and their health-care providers in the decision-making process.

Original languageEnglish (US)
Pages (from-to)1297-1306
Number of pages10
JournalJournal of the National Cancer Institute
Volume93
Issue number17
StatePublished - Sep 5 2001

Fingerprint

Mastectomy
Risk Reduction Behavior
Research
Breast Neoplasms
Health Personnel
Decision Making
Breast Self-Examination
Aftercare
Chemoprevention
Ovariectomy
Women's Health
Mammography
Tamoxifen
Breast
Psychology
Mutation

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Stefanek, M., Hartmann, L., & Nelson, W. (2001). Risk-reduction mastectomy: Clinical issues and research needs. Journal of the National Cancer Institute, 93(17), 1297-1306.

Risk-reduction mastectomy : Clinical issues and research needs. / Stefanek, Michael; Hartmann, Lynn; Nelson, Wendy.

In: Journal of the National Cancer Institute, Vol. 93, No. 17, 05.09.2001, p. 1297-1306.

Research output: Contribution to journalArticle

Stefanek, M, Hartmann, L & Nelson, W 2001, 'Risk-reduction mastectomy: Clinical issues and research needs', Journal of the National Cancer Institute, vol. 93, no. 17, pp. 1297-1306.
Stefanek, Michael ; Hartmann, Lynn ; Nelson, Wendy. / Risk-reduction mastectomy : Clinical issues and research needs. In: Journal of the National Cancer Institute. 2001 ; Vol. 93, No. 17. pp. 1297-1306.
@article{cd767844a4c64f6f9b6385c9ba593c24,
title = "Risk-reduction mastectomy: Clinical issues and research needs",
abstract = "Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer. High-risk women, including women with a strong family history of breast cancer and BRCA1/2 mutation carriers, have several clinical options: risk-reduction surgery (bilateral mastectomy and bilateral oophorectomy), surveillance (mammography, clinical breast examination, and breast self-examination), and chemoprevention (tamoxifen). We review research in a number of areas central to our understanding of RRM, including recent data on 1) the effectiveness of RRM in reducing breast cancer risk, 2) the perception of RRM among women at increased risk and health-care providers, 3) the decision-making process for follow-up care of women at high risk, and 4) satisfaction and psychological status after surgery. We suggest areas of future research to better guide high-risk women and their health-care providers in the decision-making process.",
author = "Michael Stefanek and Lynn Hartmann and Wendy Nelson",
year = "2001",
month = "9",
day = "5",
language = "English (US)",
volume = "93",
pages = "1297--1306",
journal = "Journal of the National Cancer Institute",
issn = "0027-8874",
publisher = "Oxford University Press",
number = "17",

}

TY - JOUR

T1 - Risk-reduction mastectomy

T2 - Clinical issues and research needs

AU - Stefanek, Michael

AU - Hartmann, Lynn

AU - Nelson, Wendy

PY - 2001/9/5

Y1 - 2001/9/5

N2 - Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer. High-risk women, including women with a strong family history of breast cancer and BRCA1/2 mutation carriers, have several clinical options: risk-reduction surgery (bilateral mastectomy and bilateral oophorectomy), surveillance (mammography, clinical breast examination, and breast self-examination), and chemoprevention (tamoxifen). We review research in a number of areas central to our understanding of RRM, including recent data on 1) the effectiveness of RRM in reducing breast cancer risk, 2) the perception of RRM among women at increased risk and health-care providers, 3) the decision-making process for follow-up care of women at high risk, and 4) satisfaction and psychological status after surgery. We suggest areas of future research to better guide high-risk women and their health-care providers in the decision-making process.

AB - Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer. High-risk women, including women with a strong family history of breast cancer and BRCA1/2 mutation carriers, have several clinical options: risk-reduction surgery (bilateral mastectomy and bilateral oophorectomy), surveillance (mammography, clinical breast examination, and breast self-examination), and chemoprevention (tamoxifen). We review research in a number of areas central to our understanding of RRM, including recent data on 1) the effectiveness of RRM in reducing breast cancer risk, 2) the perception of RRM among women at increased risk and health-care providers, 3) the decision-making process for follow-up care of women at high risk, and 4) satisfaction and psychological status after surgery. We suggest areas of future research to better guide high-risk women and their health-care providers in the decision-making process.

UR - http://www.scopus.com/inward/record.url?scp=0035812281&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035812281&partnerID=8YFLogxK

M3 - Article

C2 - 11535704

AN - SCOPUS:0035812281

VL - 93

SP - 1297

EP - 1306

JO - Journal of the National Cancer Institute

JF - Journal of the National Cancer Institute

SN - 0027-8874

IS - 17

ER -