Risk of deep venous thrombosis associated with chest versus arm central venous subcutaneous port catheters: A 5-year single-institution retrospective study

Philip Kuriakose, Gerardo Colon-Otero, Ricardo Paz-Fumagalli

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Abstract

PURPOSE: To determine the risk of deep venous thrombosis (DVT) in patients undergoing placement of central (chest) versus peripheral (arm) ports. MATERIALS AND METHODS: Between January 1996 and December 2000, a total of 440 implantable chest or arm ports were placed in 422 patients. Data pertaining to the first port placed for each patient was analyzed. Ports were placed for chemotherapy (n = 415) or blood transfusion (n = 7). Subset analysis was performed, taking into consideration whether patients received prophylactic or therapeutic doses of warfarin sodium (Coumadin), to determine if there was any difference in the incidence of DVT between patients undergoing some form of anticoagulation versus those undergoing none. The medical records of these patients were reviewed to determine outcome with reference to development of DVT. RESULTS: In 273 chest ports placed, there were 13 (4.8%) instances of DVT; in 149 peripheral ports, there were 17 (11.4%). Censoring data on patients receiving some form of anticoagulation, the respective incidences were eight of 245 (3.3%) and 14 of 129 (10.9%). With use of Kaplan-Meier analysis and log-rank tests to examine comparisons of interest, the probability of thrombosis occurring over a period of 180 days was higher with peripheral ports irrespective of Coumadin use (P = .007 for all patients considered, P = .002 when analyzed only for those not receiving Coumadin). The difference in incidence of thrombosis for all ports between patients receiving Coumadin versus those not receiving Coumadin was not significant. CONCLUSIONS: Compared to chest ports, peripheral ports are associated with a significantly higher incidence of DVT.

Original languageEnglish (US)
Pages (from-to)179-184
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume13
Issue number2
StatePublished - 2002

Fingerprint

Vascular Access Devices
Venous Thrombosis
Arm
Thorax
Retrospective Studies
Warfarin
Incidence
Thrombosis
Kaplan-Meier Estimate
Blood Transfusion
Medical Records
Drug Therapy

Keywords

  • Catheters and catheterization, access
  • Ports
  • Thrombosis, venous
  • Veins, access

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

@article{848450d101ea4463afc054c6b84f7269,
title = "Risk of deep venous thrombosis associated with chest versus arm central venous subcutaneous port catheters: A 5-year single-institution retrospective study",
abstract = "PURPOSE: To determine the risk of deep venous thrombosis (DVT) in patients undergoing placement of central (chest) versus peripheral (arm) ports. MATERIALS AND METHODS: Between January 1996 and December 2000, a total of 440 implantable chest or arm ports were placed in 422 patients. Data pertaining to the first port placed for each patient was analyzed. Ports were placed for chemotherapy (n = 415) or blood transfusion (n = 7). Subset analysis was performed, taking into consideration whether patients received prophylactic or therapeutic doses of warfarin sodium (Coumadin), to determine if there was any difference in the incidence of DVT between patients undergoing some form of anticoagulation versus those undergoing none. The medical records of these patients were reviewed to determine outcome with reference to development of DVT. RESULTS: In 273 chest ports placed, there were 13 (4.8{\%}) instances of DVT; in 149 peripheral ports, there were 17 (11.4{\%}). Censoring data on patients receiving some form of anticoagulation, the respective incidences were eight of 245 (3.3{\%}) and 14 of 129 (10.9{\%}). With use of Kaplan-Meier analysis and log-rank tests to examine comparisons of interest, the probability of thrombosis occurring over a period of 180 days was higher with peripheral ports irrespective of Coumadin use (P = .007 for all patients considered, P = .002 when analyzed only for those not receiving Coumadin). The difference in incidence of thrombosis for all ports between patients receiving Coumadin versus those not receiving Coumadin was not significant. CONCLUSIONS: Compared to chest ports, peripheral ports are associated with a significantly higher incidence of DVT.",
keywords = "Catheters and catheterization, access, Ports, Thrombosis, venous, Veins, access",
author = "Philip Kuriakose and Gerardo Colon-Otero and Ricardo Paz-Fumagalli",
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journal = "Journal of Vascular and Interventional Radiology",
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T1 - Risk of deep venous thrombosis associated with chest versus arm central venous subcutaneous port catheters

T2 - A 5-year single-institution retrospective study

AU - Kuriakose, Philip

AU - Colon-Otero, Gerardo

AU - Paz-Fumagalli, Ricardo

PY - 2002

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N2 - PURPOSE: To determine the risk of deep venous thrombosis (DVT) in patients undergoing placement of central (chest) versus peripheral (arm) ports. MATERIALS AND METHODS: Between January 1996 and December 2000, a total of 440 implantable chest or arm ports were placed in 422 patients. Data pertaining to the first port placed for each patient was analyzed. Ports were placed for chemotherapy (n = 415) or blood transfusion (n = 7). Subset analysis was performed, taking into consideration whether patients received prophylactic or therapeutic doses of warfarin sodium (Coumadin), to determine if there was any difference in the incidence of DVT between patients undergoing some form of anticoagulation versus those undergoing none. The medical records of these patients were reviewed to determine outcome with reference to development of DVT. RESULTS: In 273 chest ports placed, there were 13 (4.8%) instances of DVT; in 149 peripheral ports, there were 17 (11.4%). Censoring data on patients receiving some form of anticoagulation, the respective incidences were eight of 245 (3.3%) and 14 of 129 (10.9%). With use of Kaplan-Meier analysis and log-rank tests to examine comparisons of interest, the probability of thrombosis occurring over a period of 180 days was higher with peripheral ports irrespective of Coumadin use (P = .007 for all patients considered, P = .002 when analyzed only for those not receiving Coumadin). The difference in incidence of thrombosis for all ports between patients receiving Coumadin versus those not receiving Coumadin was not significant. CONCLUSIONS: Compared to chest ports, peripheral ports are associated with a significantly higher incidence of DVT.

AB - PURPOSE: To determine the risk of deep venous thrombosis (DVT) in patients undergoing placement of central (chest) versus peripheral (arm) ports. MATERIALS AND METHODS: Between January 1996 and December 2000, a total of 440 implantable chest or arm ports were placed in 422 patients. Data pertaining to the first port placed for each patient was analyzed. Ports were placed for chemotherapy (n = 415) or blood transfusion (n = 7). Subset analysis was performed, taking into consideration whether patients received prophylactic or therapeutic doses of warfarin sodium (Coumadin), to determine if there was any difference in the incidence of DVT between patients undergoing some form of anticoagulation versus those undergoing none. The medical records of these patients were reviewed to determine outcome with reference to development of DVT. RESULTS: In 273 chest ports placed, there were 13 (4.8%) instances of DVT; in 149 peripheral ports, there were 17 (11.4%). Censoring data on patients receiving some form of anticoagulation, the respective incidences were eight of 245 (3.3%) and 14 of 129 (10.9%). With use of Kaplan-Meier analysis and log-rank tests to examine comparisons of interest, the probability of thrombosis occurring over a period of 180 days was higher with peripheral ports irrespective of Coumadin use (P = .007 for all patients considered, P = .002 when analyzed only for those not receiving Coumadin). The difference in incidence of thrombosis for all ports between patients receiving Coumadin versus those not receiving Coumadin was not significant. CONCLUSIONS: Compared to chest ports, peripheral ports are associated with a significantly higher incidence of DVT.

KW - Catheters and catheterization, access

KW - Ports

KW - Thrombosis, venous

KW - Veins, access

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