Risk factors for subsequent recurrence after surgical treatment of recurrent pleomorphic adenoma of the parotid gland

Steven A. Rooker, Kathryn M. Van Abel, Linda X. Yin, Alex A. Nagelschneider, Daniel L. Price, Kerry D. Olsen, Jeffrey R. Janus, Jan L. Kasperbauer, Eric J. Moore

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Recurrent pleomorphic adenoma (PA) can be a lifelong disease, and rates of subsequent recurrence are high. Methods: Patients between 2000 and 2015 were identified. Primary outcome was subsequent recurrence after surgical salvage. Results: Twenty-seven of 84 patients developed a subsequent recurrence. Risk factors for subsequent recurrence included a higher number of previous recurrences (P <.01), worse preoperative facial nerve function (P <.01), and deep parotid lesion(s) (P <.01). Interval since last surgery was protective (P <.01), specifically >10 years since last surgery (P <.01). For patients with a >10-year interval since their last surgery, the subsequent recurrence-free rate at 10 years follow-up was 80.2% vs 31.8%. Conclusions: For patients presenting with a >10-year interval since their last surgery, subsequent recurrence rates are low, which may allow for as needed surveillance recommendations. For patients presenting with recurrent PA and ≤10 years since their last surgery, a closer surveillance is warranted.

Original languageEnglish (US)
Pages (from-to)1088-1096
Number of pages9
JournalHead and Neck
Volume43
Issue number4
DOIs
StatePublished - Apr 2021

Keywords

  • parotid
  • pleomorphic adenoma
  • recurrent
  • risk factors
  • subsequent recurrence

ASJC Scopus subject areas

  • Otorhinolaryngology

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