Right Ventricular Function in Asymptomatic Individuals with a Systemic Right Ventricle

J. Martijn Bos, Donald J. Hagler, Suchaya Silvilairat, Allison Cabalka, Patrick O'Leary, Otto Daniels, Fletcher A Jr. Miller, Theodore P. Abraham

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Background: In congenital heart defects where the morphologic right ventricle (RV) supports the systemic circulation, RV failure is common yet develops gradually. We hypothesized that patients who are asymptomatic may have unrecognized RV dysfunction. Methods: Conventional and Doppler tissue/strain echocardiography were performed on consecutive patients with asymptomatic systemic RV caused by congenitally corrected transposition of the great arteries (ccTGA) and on age-matched control subjects. RV index of myocardial performance was measured using conventional echocardiography. Longitudinal tissue velocities, strain rate, and strain of the basal RV free wall were measured using Doppler tissue/strain echocardiography and compared with nonsystemic RV of the control subjects. Results: Mean age was 39.5 ± 14.6 (n = 13) and 36 ± 24 (n = 10) years for ccTGA and control groups, respectively. Mean RV index of myocardial performance was higher in patients with ccTGA than in control subjects (0.66 ± 0.25 vs 0.28 ± 0.12, P < .001). Mean RV tissue displacement (10.8 ± 4.5 vs 20.3 ± 3.9 mm, P < .0001), peak systolic strain rate (-1.16 ± 0.3 vs -2.23 ± 0.9 s-1, P = .005), and peak systolic strain (-17.3 ± 8.0 vs -30.6 ± 11.0%, P = .008) were significantly lower in patients with ccTGA compared with control subjects, respectively. Conclusion: Patients with asymptomatic ccTGA have quantifiable RV dysfunction by echocardiography.

Original languageEnglish (US)
Pages (from-to)1033-1037
Number of pages5
JournalJournal of the American Society of Echocardiography
Volume19
Issue number8
DOIs
StatePublished - Aug 2006

Fingerprint

Right Ventricular Function
Heart Ventricles
Echocardiography
Congenital Heart Defects
Congenitally corrected transposition of the great arteries

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Bos, J. M., Hagler, D. J., Silvilairat, S., Cabalka, A., O'Leary, P., Daniels, O., ... Abraham, T. P. (2006). Right Ventricular Function in Asymptomatic Individuals with a Systemic Right Ventricle. Journal of the American Society of Echocardiography, 19(8), 1033-1037. https://doi.org/10.1016/j.echo.2006.03.007

Right Ventricular Function in Asymptomatic Individuals with a Systemic Right Ventricle. / Bos, J. Martijn; Hagler, Donald J.; Silvilairat, Suchaya; Cabalka, Allison; O'Leary, Patrick; Daniels, Otto; Miller, Fletcher A Jr.; Abraham, Theodore P.

In: Journal of the American Society of Echocardiography, Vol. 19, No. 8, 08.2006, p. 1033-1037.

Research output: Contribution to journalArticle

Bos, JM, Hagler, DJ, Silvilairat, S, Cabalka, A, O'Leary, P, Daniels, O, Miller, FAJ & Abraham, TP 2006, 'Right Ventricular Function in Asymptomatic Individuals with a Systemic Right Ventricle', Journal of the American Society of Echocardiography, vol. 19, no. 8, pp. 1033-1037. https://doi.org/10.1016/j.echo.2006.03.007
Bos, J. Martijn ; Hagler, Donald J. ; Silvilairat, Suchaya ; Cabalka, Allison ; O'Leary, Patrick ; Daniels, Otto ; Miller, Fletcher A Jr. ; Abraham, Theodore P. / Right Ventricular Function in Asymptomatic Individuals with a Systemic Right Ventricle. In: Journal of the American Society of Echocardiography. 2006 ; Vol. 19, No. 8. pp. 1033-1037.
@article{c38a50cd079f4e37a569569863dac3dc,
title = "Right Ventricular Function in Asymptomatic Individuals with a Systemic Right Ventricle",
abstract = "Background: In congenital heart defects where the morphologic right ventricle (RV) supports the systemic circulation, RV failure is common yet develops gradually. We hypothesized that patients who are asymptomatic may have unrecognized RV dysfunction. Methods: Conventional and Doppler tissue/strain echocardiography were performed on consecutive patients with asymptomatic systemic RV caused by congenitally corrected transposition of the great arteries (ccTGA) and on age-matched control subjects. RV index of myocardial performance was measured using conventional echocardiography. Longitudinal tissue velocities, strain rate, and strain of the basal RV free wall were measured using Doppler tissue/strain echocardiography and compared with nonsystemic RV of the control subjects. Results: Mean age was 39.5 ± 14.6 (n = 13) and 36 ± 24 (n = 10) years for ccTGA and control groups, respectively. Mean RV index of myocardial performance was higher in patients with ccTGA than in control subjects (0.66 ± 0.25 vs 0.28 ± 0.12, P < .001). Mean RV tissue displacement (10.8 ± 4.5 vs 20.3 ± 3.9 mm, P < .0001), peak systolic strain rate (-1.16 ± 0.3 vs -2.23 ± 0.9 s-1, P = .005), and peak systolic strain (-17.3 ± 8.0 vs -30.6 ± 11.0{\%}, P = .008) were significantly lower in patients with ccTGA compared with control subjects, respectively. Conclusion: Patients with asymptomatic ccTGA have quantifiable RV dysfunction by echocardiography.",
author = "Bos, {J. Martijn} and Hagler, {Donald J.} and Suchaya Silvilairat and Allison Cabalka and Patrick O'Leary and Otto Daniels and Miller, {Fletcher A Jr.} and Abraham, {Theodore P.}",
year = "2006",
month = "8",
doi = "10.1016/j.echo.2006.03.007",
language = "English (US)",
volume = "19",
pages = "1033--1037",
journal = "Journal of the American Society of Echocardiography",
issn = "0894-7317",
publisher = "Mosby Inc.",
number = "8",

}

TY - JOUR

T1 - Right Ventricular Function in Asymptomatic Individuals with a Systemic Right Ventricle

AU - Bos, J. Martijn

AU - Hagler, Donald J.

AU - Silvilairat, Suchaya

AU - Cabalka, Allison

AU - O'Leary, Patrick

AU - Daniels, Otto

AU - Miller, Fletcher A Jr.

AU - Abraham, Theodore P.

PY - 2006/8

Y1 - 2006/8

N2 - Background: In congenital heart defects where the morphologic right ventricle (RV) supports the systemic circulation, RV failure is common yet develops gradually. We hypothesized that patients who are asymptomatic may have unrecognized RV dysfunction. Methods: Conventional and Doppler tissue/strain echocardiography were performed on consecutive patients with asymptomatic systemic RV caused by congenitally corrected transposition of the great arteries (ccTGA) and on age-matched control subjects. RV index of myocardial performance was measured using conventional echocardiography. Longitudinal tissue velocities, strain rate, and strain of the basal RV free wall were measured using Doppler tissue/strain echocardiography and compared with nonsystemic RV of the control subjects. Results: Mean age was 39.5 ± 14.6 (n = 13) and 36 ± 24 (n = 10) years for ccTGA and control groups, respectively. Mean RV index of myocardial performance was higher in patients with ccTGA than in control subjects (0.66 ± 0.25 vs 0.28 ± 0.12, P < .001). Mean RV tissue displacement (10.8 ± 4.5 vs 20.3 ± 3.9 mm, P < .0001), peak systolic strain rate (-1.16 ± 0.3 vs -2.23 ± 0.9 s-1, P = .005), and peak systolic strain (-17.3 ± 8.0 vs -30.6 ± 11.0%, P = .008) were significantly lower in patients with ccTGA compared with control subjects, respectively. Conclusion: Patients with asymptomatic ccTGA have quantifiable RV dysfunction by echocardiography.

AB - Background: In congenital heart defects where the morphologic right ventricle (RV) supports the systemic circulation, RV failure is common yet develops gradually. We hypothesized that patients who are asymptomatic may have unrecognized RV dysfunction. Methods: Conventional and Doppler tissue/strain echocardiography were performed on consecutive patients with asymptomatic systemic RV caused by congenitally corrected transposition of the great arteries (ccTGA) and on age-matched control subjects. RV index of myocardial performance was measured using conventional echocardiography. Longitudinal tissue velocities, strain rate, and strain of the basal RV free wall were measured using Doppler tissue/strain echocardiography and compared with nonsystemic RV of the control subjects. Results: Mean age was 39.5 ± 14.6 (n = 13) and 36 ± 24 (n = 10) years for ccTGA and control groups, respectively. Mean RV index of myocardial performance was higher in patients with ccTGA than in control subjects (0.66 ± 0.25 vs 0.28 ± 0.12, P < .001). Mean RV tissue displacement (10.8 ± 4.5 vs 20.3 ± 3.9 mm, P < .0001), peak systolic strain rate (-1.16 ± 0.3 vs -2.23 ± 0.9 s-1, P = .005), and peak systolic strain (-17.3 ± 8.0 vs -30.6 ± 11.0%, P = .008) were significantly lower in patients with ccTGA compared with control subjects, respectively. Conclusion: Patients with asymptomatic ccTGA have quantifiable RV dysfunction by echocardiography.

UR - http://www.scopus.com/inward/record.url?scp=33746776824&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33746776824&partnerID=8YFLogxK

U2 - 10.1016/j.echo.2006.03.007

DO - 10.1016/j.echo.2006.03.007

M3 - Article

VL - 19

SP - 1033

EP - 1037

JO - Journal of the American Society of Echocardiography

JF - Journal of the American Society of Echocardiography

SN - 0894-7317

IS - 8

ER -