Right hepatic lobe resection and thrombocytopenia

Abimbola Adike, Jorge Rakela, Christopher Czaplicki, Adyr Moss, Elizabeth Carey

Research output: Contribution to journalArticle

Abstract

Thrombocytopenia has previously been reported after right lobe resection for organ donation. The mechanism(s) of low platelets after right hepatectomy is unclear and several hypotheses have been proposed including a decrease in thrombopoietin, and hepatic insufficiency resulting in relative portal hypertension following hepatic resection. However, there has previously not been any comparison between patients who undergo hepatic resection for neoplasia vs. for living organ donation. We compared platelet values in the postoperative period of patients who underwent right hepatectomy for living donation (n = 93) to those who underwent hepatectomy for neoplasia (n = 21). There was no significant difference in platelet values between the two groups at one month (291.2 ± 100 vs. 285.73 ± 159, p = NS), three months (223.8 ± 61 vs. 185.27 ± 80, p = NS) and at 12 months (212 ± 44 vs. 191 ± 60, p = NS). We conclude that thrombocytopenia is not uncommon following hepatic lobe resection, and is unaffected by the indication for hepatectomy.

Original languageEnglish (US)
Pages (from-to)10-11
Number of pages2
JournalAnnals of Hepatology
Volume16
Issue number1
DOIs
StatePublished - Jan 1 2017

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Hepatectomy
Thrombocytopenia
Tissue and Organ Procurement
Blood Platelets
Liver
Hepatic Insufficiency
Thrombopoietin
Portal Hypertension
Postoperative Period
Neoplasms

ASJC Scopus subject areas

  • Hepatology

Cite this

Right hepatic lobe resection and thrombocytopenia. / Adike, Abimbola; Rakela, Jorge; Czaplicki, Christopher; Moss, Adyr; Carey, Elizabeth.

In: Annals of Hepatology, Vol. 16, No. 1, 01.01.2017, p. 10-11.

Research output: Contribution to journalArticle

Adike, A, Rakela, J, Czaplicki, C, Moss, A & Carey, E 2017, 'Right hepatic lobe resection and thrombocytopenia', Annals of Hepatology, vol. 16, no. 1, pp. 10-11. https://doi.org/10.5604/16652681.1226810
Adike, Abimbola ; Rakela, Jorge ; Czaplicki, Christopher ; Moss, Adyr ; Carey, Elizabeth. / Right hepatic lobe resection and thrombocytopenia. In: Annals of Hepatology. 2017 ; Vol. 16, No. 1. pp. 10-11.
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