Rhythmic electrographic discharges during deep hypothermic circulatory arrest

Anteneh Feyissa, Alberto Pochettino, Thomas C. Bower, Gregory A. Nuttall, Jeffrey W. Britton

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: The main objective of this study is to examine the prevalence and timing of rhythmic electrographic discharges and periodic sharp transients during aortic arch repair surgeries using DHCA as detected by continuous intraoperative encephalogram (EEG) and correlate it with outcome.

METHODS: Electronic medical records and the intraoperative EEGs of 32 patients who underwent aortic arch reconstruction with DHCA were reviewed. Preoperative patient characteristics, intraoperative data, and postoperative outcomes were examined. EEGs were graded based on the frequency of sharp transients (grade 0-2) and/or the presence of rhythmic electrographic discharges (grade 3).

RESULTS: Periodic sharp transients were seen in 30/32 cases. Grade 1 and grade 2 activations were more prominent during cooling at nasopharyngeal temperature of 23.9±4.01 °C (mean±SDV). Rhythmic electrographic discharges occurred in seven patients and were exclusively seen during cooling at nasopharyngeal temperatures below 28 °C except in one case during rewarming at nasopharyngeal temperatures of 22°C. No patient with rhythmic discharges developed postoperative clinical neurologic deficit or seizures.

CONCLUSIONS: Periodic sharp transients occurred in almost all cases during induction of deep hypothermia. This activity was not associated with postoperative neurologic deficit.

SIGNIFICANCE: Clinical neurophysiologists, technicians and surgeons need to be aware that low amplitude periodic sharp transients and rhythmic electrographic discharges are common during DHCA, yet have no apparent clinical significance.

Original languageEnglish (US)
Pages (from-to)1901-1906
Number of pages6
JournalClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Volume127
Issue number3
DOIs
StatePublished - Mar 1 2016

Fingerprint

Deep Hypothermia Induced Circulatory Arrest
Neurologic Manifestations
Thoracic Aorta
Temperature
Electroencephalography
Rewarming
Electronic Health Records
Hypothermia
Seizures

Keywords

  • Aortic arch repair
  • Deep hypothermia
  • EEG
  • Intraoperative EEG monitoring
  • Rhythmic electrographic discharges
  • Sharp transients
  • Status epilepticus
  • Therapeutic hypothermia

ASJC Scopus subject areas

  • Sensory Systems
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

Rhythmic electrographic discharges during deep hypothermic circulatory arrest. / Feyissa, Anteneh; Pochettino, Alberto; Bower, Thomas C.; Nuttall, Gregory A.; Britton, Jeffrey W.

In: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, Vol. 127, No. 3, 01.03.2016, p. 1901-1906.

Research output: Contribution to journalArticle

Feyissa, Anteneh ; Pochettino, Alberto ; Bower, Thomas C. ; Nuttall, Gregory A. ; Britton, Jeffrey W. / Rhythmic electrographic discharges during deep hypothermic circulatory arrest. In: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2016 ; Vol. 127, No. 3. pp. 1901-1906.
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