Revisiting the simplified Bernoulli equation

Jeffrey J. Heys, Nicole Holyoak, Anna M. Calleja, Marek Belohlavek, Hari P. Chaliki

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Background: The assessment of the severity of aortic valve stenosis is done by either invasive catheterization or non-invasive Doppler Echocardiography in conjunction with the simplified Bernoulli equation. The catheter measurement is generally considered more accurate, but the procedure is also more likely to have dangerous complications. Objective: The focus here is on examining computational fluid dynamics as an alternative method for analyzing the echo data and determining whether it can provide results similar to the catheter measurement. Methods: An in vitro heart model with a rigid orifice is used as a first step in comparing echocardiographic data, which uses the simplified Bernoulli equation, catheterization, and echocardiographic data, which uses computational fluid dynamics (i.e., the Navier-Stokes equations). Results: For a 0.93cm2 orifice, the maximum pressure gradient predicted by either the simplified Bernoulli equation or computational fluid dynamics was not significantly different from the experimental catheter measurement (p > 0.01). For a smaller 0.52cm2 orifice, there was a small but significant difference (p < 0.01) between the simplified Bernoulli equation and the computational fluid dynamics simulation, with the computational fluid dynamics simulation giving better agreement with experimental data for some turbulence models. Conclusion: For this simplified, in vitro system, the use of computational fluid dynamics provides an improvement over the simplified Bernoulli equation with the biggest improvement being seen at higher valvular stenosis levels.

Original languageEnglish (US)
Pages (from-to)123-128
Number of pages6
JournalOpen Biomedical Engineering Journal
Volume4
DOIs
StatePublished - 2010

Keywords

  • Catheter
  • Computational fluid dynamics
  • Doppler Echocardiography
  • Turbulence
  • Valvular stenosis

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering

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