Revisiting the imaging appearance of neuromuscular choristoma versus lipomatous lesions of nerve: Nuancing the 50% rule

Nikhil K. Murthy; Kimberly K. Amrami; B. Matthew Howe; Stephen M. Broski; Jodi M. Carter; Robert J. Spinner

doi:10.1016/j.inat.2021.101322

Revisiting the imaging appearance of neuromuscular choristoma versus lipomatous lesions of nerve: Nuancing the 50% rule

Nikhil K. Murthy, Kimberly K. Amrami, B. Matthew Howe, Stephen M. Broski, Jodi M. Carter, Robert J. Spinner

Research output: Contribution to journal › Article › peer-review

Abstract

Neuromuscular choristoma (NMC) is a rare benign peripheral nerve lesion characterized by mature skeletal or smooth muscle admixed with nerve fibers whereas lipomatosis of nerve (LN) is characterized by adipose tissue. We describe a case of a 49-year-old woman with a fat-containing mass associated with the brachial plexus appearing as a hibernoma, atypical LN, or atypical lipomatous tumor. Biopsy revealed pathognomonic histologic features of NMC. We suggest the 50% rule previously proposed to distinguish NMC from other fatty lesions be applied to the portion of the lesion with soft tissue elements, and not the lesion as a whole.

Original language	English (US)
Article number	101322
Journal	Interdisciplinary Neurosurgery: Advanced Techniques and Case Management
Volume	26
DOIs	https://doi.org/10.1016/j.inat.2021.101322
State	Published - Dec 2021

Keywords

Fibrolipomatous hamartoma
Lipomatosis
Magnetic resonance imaging
Neuromuscular choristoma
Peripheral nerve

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1016/j.inat.2021.101322

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title = "Revisiting the imaging appearance of neuromuscular choristoma versus lipomatous lesions of nerve: Nuancing the 50% rule",

abstract = "Neuromuscular choristoma (NMC) is a rare benign peripheral nerve lesion characterized by mature skeletal or smooth muscle admixed with nerve fibers whereas lipomatosis of nerve (LN) is characterized by adipose tissue. We describe a case of a 49-year-old woman with a fat-containing mass associated with the brachial plexus appearing as a hibernoma, atypical LN, or atypical lipomatous tumor. Biopsy revealed pathognomonic histologic features of NMC. We suggest the 50% rule previously proposed to distinguish NMC from other fatty lesions be applied to the portion of the lesion with soft tissue elements, and not the lesion as a whole.",

keywords = "Fibrolipomatous hamartoma, Lipomatosis, Magnetic resonance imaging, Neuromuscular choristoma, Peripheral nerve",

author = "Murthy, {Nikhil K.} and Amrami, {Kimberly K.} and {Matthew Howe}, B. and Broski, {Stephen M.} and Carter, {Jodi M.} and Spinner, {Robert J.}",

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T1 - Revisiting the imaging appearance of neuromuscular choristoma versus lipomatous lesions of nerve

T2 - Nuancing the 50% rule

AU - Murthy, Nikhil K.

AU - Amrami, Kimberly K.

AU - Matthew Howe, B.

AU - Broski, Stephen M.

AU - Carter, Jodi M.

AU - Spinner, Robert J.

PY - 2021/12

Y1 - 2021/12

N2 - Neuromuscular choristoma (NMC) is a rare benign peripheral nerve lesion characterized by mature skeletal or smooth muscle admixed with nerve fibers whereas lipomatosis of nerve (LN) is characterized by adipose tissue. We describe a case of a 49-year-old woman with a fat-containing mass associated with the brachial plexus appearing as a hibernoma, atypical LN, or atypical lipomatous tumor. Biopsy revealed pathognomonic histologic features of NMC. We suggest the 50% rule previously proposed to distinguish NMC from other fatty lesions be applied to the portion of the lesion with soft tissue elements, and not the lesion as a whole.

AB - Neuromuscular choristoma (NMC) is a rare benign peripheral nerve lesion characterized by mature skeletal or smooth muscle admixed with nerve fibers whereas lipomatosis of nerve (LN) is characterized by adipose tissue. We describe a case of a 49-year-old woman with a fat-containing mass associated with the brachial plexus appearing as a hibernoma, atypical LN, or atypical lipomatous tumor. Biopsy revealed pathognomonic histologic features of NMC. We suggest the 50% rule previously proposed to distinguish NMC from other fatty lesions be applied to the portion of the lesion with soft tissue elements, and not the lesion as a whole.

KW - Fibrolipomatous hamartoma

KW - Lipomatosis

KW - Magnetic resonance imaging

KW - Neuromuscular choristoma

KW - Peripheral nerve

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Revisiting the imaging appearance of neuromuscular choristoma versus lipomatous lesions of nerve: Nuancing the 50% rule

Abstract

Keywords

ASJC Scopus subject areas

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