Review of Select Sleep Medicine Pharmacology: Treatments of Hypersomnias and Parasomnia

Kimberly Johnson; Meghna P. Mansukhani; Bhanu Prakash Kolla

doi:10.1016/B978-0-12-820472-6.00163-8

Review of Select Sleep Medicine Pharmacology: Treatments of Hypersomnias and Parasomnia

Kimberly Johnson, Meghna P. Mansukhani, Bhanu Prakash Kolla

Family Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The field of sleep medicine has made several strides forward in the understanding and treatment of various sleep disorders. These discoveries have further highlighted the intricate nature of sleep regulation and the multiple concerted processes required for normal sleep behavior. In this chapter, we will review current pathophysiologic understanding and available treatments for the conditions of hypersomnia and parasomnias. In recent years, advances in the understanding of hypersomnia have been particularly exciting with the discovery of hypocretin/orexin signaling and several newly FDA-approved pharmaceuticals for hypersomnia treatment. Each section concludes with a summary of the available pharmaceuticals, and comprehensive table is provided at the end of the chapter.

Original language	English (US)
Title of host publication	Comprehensive Pharmacology
Publisher	Elsevier
Pages	179-199
Number of pages	21
Volume	3
ISBN (Electronic)	9780128204726
DOIs	https://doi.org/10.1016/B978-0-12-820472-6.00163-8
State	Published - Jan 1 2022

Keywords

Disorders of arousal
Hypersomnia
Idiopathic hypersomnia
Kleine-Levin syndrome
Medications
Narcolepsy
NREM-related parasomnias
Parasomnias
REM sleep behavior disorder
REM-related parasomnias

ASJC Scopus subject areas

Medicine(all)
Pharmacology, Toxicology and Pharmaceutics(all)

Access to Document

10.1016/B978-0-12-820472-6.00163-8

Cite this

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abstract = "The field of sleep medicine has made several strides forward in the understanding and treatment of various sleep disorders. These discoveries have further highlighted the intricate nature of sleep regulation and the multiple concerted processes required for normal sleep behavior. In this chapter, we will review current pathophysiologic understanding and available treatments for the conditions of hypersomnia and parasomnias. In recent years, advances in the understanding of hypersomnia have been particularly exciting with the discovery of hypocretin/orexin signaling and several newly FDA-approved pharmaceuticals for hypersomnia treatment. Each section concludes with a summary of the available pharmaceuticals, and comprehensive table is provided at the end of the chapter.",

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KW - Disorders of arousal

KW - Hypersomnia

KW - Idiopathic hypersomnia

KW - Kleine-Levin syndrome

KW - Medications

KW - Narcolepsy

KW - NREM-related parasomnias

KW - Parasomnias

KW - REM sleep behavior disorder

KW - REM-related parasomnias

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EP - 199

BT - Comprehensive Pharmacology

PB - Elsevier

ER -

Review of Select Sleep Medicine Pharmacology: Treatments of Hypersomnias and Parasomnia

Abstract

Keywords

ASJC Scopus subject areas

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