Review of contemporaneous mycosis fungoides and B-cell malignancy at Mayo Clinic

Elise Herro, David J. DiCaudo, Mark D.P. Davis, Amy L. Weaver, David L. Swanson

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Background: Having either mycosis fungoides or B-cell lymphoma may predispose a patient to the other. Objective: We sought to determine whether the contemporaneous occurrence of the two malignancies is greater than chance and to investigate possible risk factors for the second malignancy. Methods: We retrospectively reviewed the records of patients with contemporaneous mycosis fungoides and B-cell lymphoma seen between 1990 and 2007 at Mayo Clinic, Rochester, MN, or at Mayo Clinic, Scottsdale, AZ. Results: In all, 23 patients had contemporaneous mycosis fungoides and B-cell malignancy. The first diagnosis was mycosis fungoides in 10 patients and B-cell lymphoma in 7; in 6 patients, the diseases were diagnosed simultaneously. No therapeutic factors could account for a predisposition to a second malignancy. Limitations: Retrospective design, referral center, and small sample size are limitations. Conclusion: Mycosis fungoides and B-cell lymphoma are unlikely to occur contemporaneously by chance, but no factor obviously predisposes a patient with one malignancy to development of the second.

Original languageEnglish (US)
Pages (from-to)271-275
Number of pages5
JournalJournal of the American Academy of Dermatology
Volume61
Issue number2
DOIs
StatePublished - Aug 1 2009

Keywords

  • B-cell lymphoma
  • Sézary syndrome
  • cutaneous T-cell lymphoma
  • mycosis fungoides

ASJC Scopus subject areas

  • Dermatology

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