Review article: Cytokines and cancer anorexia cachexia syndrome

Nabila Bennani, Mellar P. Davis

Research output: Contribution to journalReview article

50 Scopus citations

Abstract

Cancer anorexia cachexia syndrome is frequent yet still a not well understood cancer-related problem. The pathophysiology of cancer cachexia is multifactorial. It is suggested to be the result of tumor-host interactions and studies of the disturbances seen during cancer anorexia cachexia syndrome, such as anorexia, hyper-metabolism, tissue wasting, metabolic abnormalities, and hormonal changes, all point to the involvement in one way or another of one key factor: cytokines. The purpose of this review is to summarize the latest developments in the field of cytokines and their role in cancer anorexia cachexia syndrome. The emphasis is on the role of cytokines in anorexia and tissue wasting.

Original languageEnglish (US)
Pages (from-to)407-411
Number of pages5
JournalAmerican Journal of Hospice and Palliative Medicine
Volume25
Issue number5
DOIs
StatePublished - Oct 1 2008
Externally publishedYes

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Keywords

  • Anorexia
  • Cancer
  • Cancer-related cachexia
  • Cytokines
  • Tissue wasting

ASJC Scopus subject areas

  • Medicine(all)

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