Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells

M. A. Higman, John D Port, N. J. Beauchamp, A. R. Chen

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

We report a case of posterior reversible leukoencephalopathy (PRL) following the infusion of dimethylsulfoxide (DMSO) cryopreserved autologous stem cells in the setting of myeloablative chemotherapy in a patient with recurrent Ewing's sarcoma. Magnetic resonance (MR) imaging revealed white matter changes which resolved over the next 2 months.

Original languageEnglish (US)
Pages (from-to)797-800
Number of pages4
JournalBone Marrow Transplantation
Volume26
Issue number7
StatePublished - 2000
Externally publishedYes

Fingerprint

Leukoencephalopathies
Ewing's Sarcoma
Dimethyl Sulfoxide
Stem Cells
Magnetic Resonance Imaging
Drug Therapy
White Matter

Keywords

  • DMSO
  • Leukoencephalopathy
  • MRI
  • Reversible
  • Stem cell infusion

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells. / Higman, M. A.; Port, John D; Beauchamp, N. J.; Chen, A. R.

In: Bone Marrow Transplantation, Vol. 26, No. 7, 2000, p. 797-800.

Research output: Contribution to journalArticle

Higman, M. A. ; Port, John D ; Beauchamp, N. J. ; Chen, A. R. / Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells. In: Bone Marrow Transplantation. 2000 ; Vol. 26, No. 7. pp. 797-800.
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