Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells

M. A. Higman; J. D. Port; N. J. Beauchamp; A. R. Chen

doi:10.1038/sj.bmt.1702589

Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells

M. A. Higman, J. D. Port, N. J. Beauchamp, A. R. Chen

Radiology

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

We report a case of posterior reversible leukoencephalopathy (PRL) following the infusion of dimethylsulfoxide (DMSO) cryopreserved autologous stem cells in the setting of myeloablative chemotherapy in a patient with recurrent Ewing's sarcoma. Magnetic resonance (MR) imaging revealed white matter changes which resolved over the next 2 months.

Original language	English (US)
Pages (from-to)	797-800
Number of pages	4
Journal	Bone Marrow Transplantation
Volume	26
Issue number	7
DOIs	https://doi.org/10.1038/sj.bmt.1702589
State	Published - 2000

Keywords

DMSO
Leukoencephalopathy
MRI
Reversible
Stem cell infusion

ASJC Scopus subject areas

Hematology
Transplantation

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10.1038/sj.bmt.1702589

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abstract = "We report a case of posterior reversible leukoencephalopathy (PRL) following the infusion of dimethylsulfoxide (DMSO) cryopreserved autologous stem cells in the setting of myeloablative chemotherapy in a patient with recurrent Ewing's sarcoma. Magnetic resonance (MR) imaging revealed white matter changes which resolved over the next 2 months.",

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AB - We report a case of posterior reversible leukoencephalopathy (PRL) following the infusion of dimethylsulfoxide (DMSO) cryopreserved autologous stem cells in the setting of myeloablative chemotherapy in a patient with recurrent Ewing's sarcoma. Magnetic resonance (MR) imaging revealed white matter changes which resolved over the next 2 months.

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KW - Leukoencephalopathy

KW - MRI

KW - Reversible

KW - Stem cell infusion

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Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells

Abstract

Keywords

ASJC Scopus subject areas

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