Revascularization in Patients With Severe Left Ventricular Dysfunction: Is the Assessment of Viability Still Viable?

Nandan S. Anavekar; Panithaya Chareonthaitawee; Jagat Narula; Bernard J. Gersh

doi:10.1016/j.jacc.2016.03.571

Revascularization in Patients With Severe Left Ventricular Dysfunction: Is the Assessment of Viability Still Viable?

Nandan S. Anavekar, Panithaya Chareonthaitawee, Jagat Narula, Bernard J. Gersh

Cardiovascular Medicine

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

Myocardial viability assessment is typically reserved for patients with coronary artery disease and significant left ventricular dysfunction. In this setting, there is myocardial adaptation to an altered physiological state that is potentially reversible. Imaging can characterize different parameters of cardiac function; however, despite previously published appraisals of different imaging modalities, there is still uncertainty regarding the role of these tests in clinical practice. The purpose of this review is to reflect on the physiological basis of myocardial viability, discuss the imaging tests available that characterize myocardial viability, and summarize the current published reports on the use of these tests in clinical practice.

Original language	English (US)
Pages (from-to)	2874-2887
Number of pages	14
Journal	Journal of the American College of Cardiology
Volume	67
Issue number	24
DOIs	https://doi.org/10.1016/j.jacc.2016.03.571
State	Published - Jun 21 2016

Keywords

coronary artery bypass graft
coronary artery disease
myocardial hibernation
myocardial ischemia
myocardial stunning

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.jacc.2016.03.571

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title = "Revascularization in Patients With Severe Left Ventricular Dysfunction: Is the Assessment of Viability Still Viable?",

abstract = "Myocardial viability assessment is typically reserved for patients with coronary artery disease and significant left ventricular dysfunction. In this setting, there is myocardial adaptation to an altered physiological state that is potentially reversible. Imaging can characterize different parameters of cardiac function; however, despite previously published appraisals of different imaging modalities, there is still uncertainty regarding the role of these tests in clinical practice. The purpose of this review is to reflect on the physiological basis of myocardial viability, discuss the imaging tests available that characterize myocardial viability, and summarize the current published reports on the use of these tests in clinical practice.",

keywords = "coronary artery bypass graft, coronary artery disease, myocardial hibernation, myocardial ischemia, myocardial stunning",

author = "Anavekar, {Nandan S.} and Panithaya Chareonthaitawee and Jagat Narula and Gersh, {Bernard J.}",

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T2 - Is the Assessment of Viability Still Viable?

AU - Anavekar, Nandan S.

AU - Chareonthaitawee, Panithaya

AU - Narula, Jagat

AU - Gersh, Bernard J.

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N2 - Myocardial viability assessment is typically reserved for patients with coronary artery disease and significant left ventricular dysfunction. In this setting, there is myocardial adaptation to an altered physiological state that is potentially reversible. Imaging can characterize different parameters of cardiac function; however, despite previously published appraisals of different imaging modalities, there is still uncertainty regarding the role of these tests in clinical practice. The purpose of this review is to reflect on the physiological basis of myocardial viability, discuss the imaging tests available that characterize myocardial viability, and summarize the current published reports on the use of these tests in clinical practice.

AB - Myocardial viability assessment is typically reserved for patients with coronary artery disease and significant left ventricular dysfunction. In this setting, there is myocardial adaptation to an altered physiological state that is potentially reversible. Imaging can characterize different parameters of cardiac function; however, despite previously published appraisals of different imaging modalities, there is still uncertainty regarding the role of these tests in clinical practice. The purpose of this review is to reflect on the physiological basis of myocardial viability, discuss the imaging tests available that characterize myocardial viability, and summarize the current published reports on the use of these tests in clinical practice.

KW - coronary artery bypass graft

KW - coronary artery disease

KW - myocardial hibernation

KW - myocardial ischemia

KW - myocardial stunning

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Revascularization in Patients With Severe Left Ventricular Dysfunction: Is the Assessment of Viability Still Viable?

Abstract

Keywords

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