Retransplantation for donor-derived neuroendocrine tumor

Rehana Begum, Denise Harnois, Raj Satyanarayana, Murli Krishna, Kevin C. Halling, George P. Kim, Justin H. Nguyen, Andrew P. Keaveny

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Although tumor transmission through liver transplantation (LT) is a rare occurrence, the consequences can be devastating, even when a very aggressive management approach is adopted. We report the case of a donor-derived small cell neuroendocrine tumor (NET) in a patient who underwent LT for cholangiocarcinoma. Despite locoregional therapy, chemotherapy and ultimately retransplantation, the patient died from metastases. The high grade nature of the NET was the most important determinant of prognosis in this case. Our experience suggests that retransplantation for donor-derived NET should only be considered when tumor biology is favorable.

Original languageEnglish (US)
Pages (from-to)83-87
Number of pages5
JournalLiver Transplantation
Volume17
Issue number1
DOIs
StatePublished - Jan 1 2011

ASJC Scopus subject areas

  • Surgery
  • Hepatology
  • Transplantation

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  • Cite this

    Begum, R., Harnois, D., Satyanarayana, R., Krishna, M., Halling, K. C., Kim, G. P., Nguyen, J. H., & Keaveny, A. P. (2011). Retransplantation for donor-derived neuroendocrine tumor. Liver Transplantation, 17(1), 83-87. https://doi.org/10.1002/lt.22196