Retransplantation for donor-derived neuroendocrine tumor

Rehana Begum, Denise Harnois, Raj Satyanarayana, Murli Krishna, Kevin C. Halling, George P. Kim, Justin H Nguyen, Andrew P. Keaveny

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Although tumor transmission through liver transplantation (LT) is a rare occurrence, the consequences can be devastating, even when a very aggressive management approach is adopted. We report the case of a donor-derived small cell neuroendocrine tumor (NET) in a patient who underwent LT for cholangiocarcinoma. Despite locoregional therapy, chemotherapy and ultimately retransplantation, the patient died from metastases. The high grade nature of the NET was the most important determinant of prognosis in this case. Our experience suggests that retransplantation for donor-derived NET should only be considered when tumor biology is favorable.

Original languageEnglish (US)
Pages (from-to)83-87
Number of pages5
JournalLiver Transplantation
Volume17
Issue number1
DOIs
StatePublished - Jan 2011

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Neuroendocrine Tumors
Tissue Donors
Liver Transplantation
Cholangiocarcinoma
Neoplasms
Neoplasm Metastasis
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Hepatology

Cite this

Begum, R., Harnois, D., Satyanarayana, R., Krishna, M., Halling, K. C., Kim, G. P., ... Keaveny, A. P. (2011). Retransplantation for donor-derived neuroendocrine tumor. Liver Transplantation, 17(1), 83-87. https://doi.org/10.1002/lt.22196

Retransplantation for donor-derived neuroendocrine tumor. / Begum, Rehana; Harnois, Denise; Satyanarayana, Raj; Krishna, Murli; Halling, Kevin C.; Kim, George P.; Nguyen, Justin H; Keaveny, Andrew P.

In: Liver Transplantation, Vol. 17, No. 1, 01.2011, p. 83-87.

Research output: Contribution to journalArticle

Begum, R, Harnois, D, Satyanarayana, R, Krishna, M, Halling, KC, Kim, GP, Nguyen, JH & Keaveny, AP 2011, 'Retransplantation for donor-derived neuroendocrine tumor', Liver Transplantation, vol. 17, no. 1, pp. 83-87. https://doi.org/10.1002/lt.22196
Begum R, Harnois D, Satyanarayana R, Krishna M, Halling KC, Kim GP et al. Retransplantation for donor-derived neuroendocrine tumor. Liver Transplantation. 2011 Jan;17(1):83-87. https://doi.org/10.1002/lt.22196
Begum, Rehana ; Harnois, Denise ; Satyanarayana, Raj ; Krishna, Murli ; Halling, Kevin C. ; Kim, George P. ; Nguyen, Justin H ; Keaveny, Andrew P. / Retransplantation for donor-derived neuroendocrine tumor. In: Liver Transplantation. 2011 ; Vol. 17, No. 1. pp. 83-87.
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