Results of percutaneous transluminal coronary angioplasty for angina pectoris early after acute myocardial infarction

Geoffrey W. Holt, Bernard J. Gersh, David Holmes, Ronald E. Vlietstra, John F. Bresnahan, Guy S. Reeder, Hugh C. Smith

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Between May 1980 and July 1985, 70 patients underwent percutaneous transluminal coronary angioplasty (PTCA) for angina occurring 24 hours after and within 30 days of acute myocardial infarction (32 with Q-wave infarction and 38 with non-Q-wave infarction). One-vessel disease was present in 42 (60%) and multivessel in 28 (40%); the mean ejection fraction was 0.56 (≥0.50 in 77% of patients). PTCA was successful in 56 patients (80%) and after introduction of steerable dilating systems in February 1983 this rate became 86%. The success rate for complete occlusions was 76%. The interval from myocardial infarction to PTCA was similar in patients with successful dilation (12.7 ± 8.1 days) and those without (13.4 ± 8.0 days). PTCA failed in 14 patients (20%); 8 underwent emergency coronary artery bypass for acute occlusion and 4 of 6 patients whose lesions could not be crossed had elective bypass surgery. There was 1 operative death. No patient sustained a Q-wave infarction. Three patients had non-Q-wave infarctions after technically successful PTCAs. Mean follow-up was 27 months (6 to 67 months). Of the 56 patients successfully dilated, 14 (25%) had 15 cardiac events during follow-up: death (1), non-Q-wave infarction (2), repeat PTCA (7), coronary bypass (4) and recurrence of severe angina (1). The cumulative mortality was 3% and the reinfarction rate was 7% (no Q-wave reinfarctions). Forty-two (60%) of the 70 patients were free of complicating events acutely and during follow-up. In patients with angina early after infarction, PTCA appears to be effective. However, the rate of subsequent interventions is high and the natural history of a similar patient population is unkown.

Original languageEnglish (US)
Pages (from-to)1238-1242
Number of pages5
JournalThe American journal of cardiology
Volume61
Issue number15
DOIs
StatePublished - Jun 1 1988

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Coronary Balloon Angioplasty
Angina Pectoris
Myocardial Infarction
Infarction
Natural History
Coronary Artery Bypass
Dilatation
Emergencies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Results of percutaneous transluminal coronary angioplasty for angina pectoris early after acute myocardial infarction. / Holt, Geoffrey W.; Gersh, Bernard J.; Holmes, David; Vlietstra, Ronald E.; Bresnahan, John F.; Reeder, Guy S.; Smith, Hugh C.

In: The American journal of cardiology, Vol. 61, No. 15, 01.06.1988, p. 1238-1242.

Research output: Contribution to journalArticle

Holt, Geoffrey W. ; Gersh, Bernard J. ; Holmes, David ; Vlietstra, Ronald E. ; Bresnahan, John F. ; Reeder, Guy S. ; Smith, Hugh C. / Results of percutaneous transluminal coronary angioplasty for angina pectoris early after acute myocardial infarction. In: The American journal of cardiology. 1988 ; Vol. 61, No. 15. pp. 1238-1242.
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abstract = "Between May 1980 and July 1985, 70 patients underwent percutaneous transluminal coronary angioplasty (PTCA) for angina occurring 24 hours after and within 30 days of acute myocardial infarction (32 with Q-wave infarction and 38 with non-Q-wave infarction). One-vessel disease was present in 42 (60{\%}) and multivessel in 28 (40{\%}); the mean ejection fraction was 0.56 (≥0.50 in 77{\%} of patients). PTCA was successful in 56 patients (80{\%}) and after introduction of steerable dilating systems in February 1983 this rate became 86{\%}. The success rate for complete occlusions was 76{\%}. The interval from myocardial infarction to PTCA was similar in patients with successful dilation (12.7 ± 8.1 days) and those without (13.4 ± 8.0 days). PTCA failed in 14 patients (20{\%}); 8 underwent emergency coronary artery bypass for acute occlusion and 4 of 6 patients whose lesions could not be crossed had elective bypass surgery. There was 1 operative death. No patient sustained a Q-wave infarction. Three patients had non-Q-wave infarctions after technically successful PTCAs. Mean follow-up was 27 months (6 to 67 months). Of the 56 patients successfully dilated, 14 (25{\%}) had 15 cardiac events during follow-up: death (1), non-Q-wave infarction (2), repeat PTCA (7), coronary bypass (4) and recurrence of severe angina (1). The cumulative mortality was 3{\%} and the reinfarction rate was 7{\%} (no Q-wave reinfarctions). Forty-two (60{\%}) of the 70 patients were free of complicating events acutely and during follow-up. In patients with angina early after infarction, PTCA appears to be effective. However, the rate of subsequent interventions is high and the natural history of a similar patient population is unkown.",
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