Results of conversion from cyclosporine to azathioprine in cadaveric renal transplantation

T. A. Gonwa, D. D. Nghiem, J. A. Schulak, R. J. Corry

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Between December 1983 and August 1985, 110 cadaver transplants were performed at our institution. All were started on cyclosporine (CsA) and prednisone (P) for immunosuppressive therapy. Of the 110 patients, 46 were converted from CsA to azathioprine (AZA) for a variety of reasons (cost, toxicity, patient preference, prolonged dysfunction posttransplant, or nonresponsive rejection). The course and outcome of these patients are described. The only group of patients who had consistent benefit and stable course following the CsA-to-AZA switch were primary cadaver transplants with stable renal function (serum creatinine less than 2 mg/dl) who were converted an average of 7.97 months posttransplant. All other groups of patients had severe problems or graft loss postconversion.

Original languageEnglish (US)
Pages (from-to)225-228
Number of pages4
JournalTransplantation
Volume43
Issue number2
StatePublished - 1987
Externally publishedYes

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Azathioprine
Kidney Transplantation
Cyclosporine
Transplants
Cadaver
Patient Preference
Immunosuppressive Agents
Prednisone
Creatinine
Kidney
Costs and Cost Analysis
Serum
Therapeutics

ASJC Scopus subject areas

  • Immunology
  • Transplantation

Cite this

Gonwa, T. A., Nghiem, D. D., Schulak, J. A., & Corry, R. J. (1987). Results of conversion from cyclosporine to azathioprine in cadaveric renal transplantation. Transplantation, 43(2), 225-228.

Results of conversion from cyclosporine to azathioprine in cadaveric renal transplantation. / Gonwa, T. A.; Nghiem, D. D.; Schulak, J. A.; Corry, R. J.

In: Transplantation, Vol. 43, No. 2, 1987, p. 225-228.

Research output: Contribution to journalArticle

Gonwa, TA, Nghiem, DD, Schulak, JA & Corry, RJ 1987, 'Results of conversion from cyclosporine to azathioprine in cadaveric renal transplantation', Transplantation, vol. 43, no. 2, pp. 225-228.
Gonwa, T. A. ; Nghiem, D. D. ; Schulak, J. A. ; Corry, R. J. / Results of conversion from cyclosporine to azathioprine in cadaveric renal transplantation. In: Transplantation. 1987 ; Vol. 43, No. 2. pp. 225-228.
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