Resting state functional MRI in Alzheimer's disease

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Abstract

Resting-state functional magnetic resonance imaging (fMRI) is emerging as an interesting biomarker for measuring connectivity of the brain in patients with Alzheimer's disease (AD). In this review, we discuss the origins of resting-state fMRI, common methodologies used to extract information from these four-dimensional fMRI scans, and important considerations for the analysis of these scans. Then we present the current state of knowledge in this area by summarizing various AD resting-state fMRI studies presented in the first section and end with a discussion of future developments and open questions in the field.

Original languageEnglish (US)
Article number2
JournalAlzheimer's Research and Therapy
Volume4
Issue number1
DOIs
StatePublished - 2012

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Alzheimer Disease
Magnetic Resonance Imaging
Biomarkers
Brain

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Cognitive Neuroscience

Cite this

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