Restenosis after percutaneous transluminal coronary angioplasty (PTCA): A report from the PTCA registry of the national heart, lung, and blood institute

David Holmes, Ronald E. Vlietstra, Hugh C. Smith, George W. Vetrovec, Kenneth M. Kent, Michael J. Cowley, David P. Faxon, Andreas R. Gruentzig, Sheryl F. Kelsey, Katherine M. Detre, Mark J. Van Raden, Michael B. Mock

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Abstract

The results of follow-up angiography in patients from 27 clinical centers enrolled in the PTCA Registry were analyzed to evaluate restenosis after PTCA. Of 665 patients with successful PTCA, 557 (84%) had follow-up angiography (median follow-up 188 days). Restenosis, defined as an increase of at least 30% from the immediate post-PTCA stenosis to the follow-up stenosis or a loss of at least 50% of the gain achieved at PTCA, was seen in 187 patients (33.6%). The incidence of restenosis in patients who underwent follow-up angiography was highest within the first 5 months after PTCA. Restenosis was found in 56% of patients with definite or probable angina after PTCA and in 14% of patients without angina after PTCA. Twenty-four percent of patients with restenosis did not have either definite or probable angina. Multivariate analysis selected 4 factors associated with increased rate of restenosis: male sex, PTCA of bypass graft stenosis, severity of angina before PTCA and no history of MI before PTCA.

Original languageEnglish (US)
JournalThe American journal of cardiology
Volume53
Issue number12
DOIs
StatePublished - Jun 15 1984
Externally publishedYes

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Holmes, D., Vlietstra, R. E., Smith, H. C., Vetrovec, G. W., Kent, K. M., Cowley, M. J., Faxon, D. P., Gruentzig, A. R., Kelsey, S. F., Detre, K. M., Van Raden, M. J., & Mock, M. B. (1984). Restenosis after percutaneous transluminal coronary angioplasty (PTCA): A report from the PTCA registry of the national heart, lung, and blood institute. The American journal of cardiology, 53(12). https://doi.org/10.1016/0002-9149(84)90752-5