Response of Primary Hepatic Amyloidosis to Melphalan and Prednisone: A Case Report and Review of the Literature

MORIE A. GERTZ; ROBERT A. KYLE

doi:10.1016/S0025-6196(12)61853-9

Response of Primary Hepatic Amyloidosis to Melphalan and Prednisone: A Case Report and Review of the Literature

MORIE A. GERTZ, ROBERT A. KYLE

Hematology

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

We report the first case of biopsy-proven primary hepatic amyloidosis in which histologic regression was demonstrated after therapy with melphalan and prednisone. On the basis of the cumulative reported experience regarding the treatment of this rare plasma cell dyscrasia, we recommend a trial of cytotoxic therapy for patients with primary hepatic amyloidosis.

Original language	English (US)
Pages (from-to)	218-223
Number of pages	6
Journal	Mayo Clinic proceedings
Volume	61
Issue number	3
DOIs	https://doi.org/10.1016/S0025-6196(12)61853-9
State	Published - 1986

ASJC Scopus subject areas

Medicine(all)

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10.1016/S0025-6196(12)61853-9

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title = "Response of Primary Hepatic Amyloidosis to Melphalan and Prednisone: A Case Report and Review of the Literature",

abstract = "We report the first case of biopsy-proven primary hepatic amyloidosis in which histologic regression was demonstrated after therapy with melphalan and prednisone. On the basis of the cumulative reported experience regarding the treatment of this rare plasma cell dyscrasia, we recommend a trial of cytotoxic therapy for patients with primary hepatic amyloidosis.",

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AB - We report the first case of biopsy-proven primary hepatic amyloidosis in which histologic regression was demonstrated after therapy with melphalan and prednisone. On the basis of the cumulative reported experience regarding the treatment of this rare plasma cell dyscrasia, we recommend a trial of cytotoxic therapy for patients with primary hepatic amyloidosis.

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Response of Primary Hepatic Amyloidosis to Melphalan and Prednisone: A Case Report and Review of the Literature

Abstract

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