Respiratory syncytial virus pneumonitis-induced diffuse alveolar damage in an autologous bone marrow transplant recipient

Svetomir N. Markovic, Arun Adlakha, Thomas F. Smith, Randall C. Walker

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A 24-year-old woman with recurrent Hodgkin's lymphoma, stage IIB nodular sclerosing type, underwent an autologous bone marrow transplantation. Forty- five days after transplantation, an upper respiratory tract infection developed that progressed to respiratory distress necessitating mechanical ventilation. An open-lung biopsy demonstrated diffuse alveolar damage. After an extensive search for the cause of the respiratory compromise, we detected respiratory syncytial virus in a bronchoalveolar lavage specimen. The patient was immediately treated with aerosolized ribavirin and intravenous immunoglobulin; her symptoms resolved, and she was extubated 4 days after initiation of therapy.

Original languageEnglish (US)
Pages (from-to)153-156
Number of pages4
JournalMayo Clinic proceedings
Volume73
Issue number2
DOIs
StatePublished - 1998

ASJC Scopus subject areas

  • Medicine(all)

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