Resolution of neuropsychological and FDG-PET abnormalities in a patient with neuropsychiatric systemic lupus erythematosus

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Many patients with systemic lupus erythematosus have central nervous system involvement. Routine diagnostic studies may not yield evidence of neuropsychiatric dysfunction and are therefore not useful as objective measures to monitor treatment response. We present a case of a 64-year-old woman whom we diagnosed with systemic lupus erythematosus by the American College of Rheumatology criteria after she reported recent cognitive decline. Neuropsychological assessment showed prominent deficits, and an F-18 fluorodeoxyglucose positron emission tomography scan of the brain showed significant abnormalities. Both the neuropsychiatric and scan abnormalities improved dramatically with immunosuppressive treatment. F-18 fluorodeoxyglucose positron emission tomography shows promise in the diagnosis and treatment monitoring of patients who have lupus with neuropsychiatric involvement.

Original languageEnglish (US)
Pages (from-to)161-166
Number of pages6
JournalCognitive and Behavioral Neurology
Volume26
Issue number3
DOIs
StatePublished - Sep 1 2013

Keywords

  • PET
  • mycophenolate
  • neuropsychiatric
  • neuropsychological
  • systemic lupus erythematosus

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Cognitive Neuroscience
  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Resolution of neuropsychological and FDG-PET abnormalities in a patient with neuropsychiatric systemic lupus erythematosus'. Together they form a unique fingerprint.

Cite this