Resection of ‘recurrent’ colorectal metastases to the liver

Florencia Que, D. M. Nagorney

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Hepatic resection is the only treatment for patients with colorectal cancer metastatic to the liver that has resulted in long‐term survival. This apparent efficacy of hepatectomy has prompted efforts to expand the surgical approach for disease progression within the liver. A review of personal experience and of the literature was performed in an attempt to define the role of surgery for disease progression. Twenty‐one patients who underwent hepatic resection between 1983 and 1991 for isolated disease progression in the liver were retrospectively reviewed. The median follow‐up of patients still alive was 1.7 years (range 4 months to 4.5 years). The median survival from the date of repeat hepatic resection was 3.4 years with an estimated actuarial survival rate of 43 per cent at 4 years. These patients experienced no significant morbidity and the mortality rate was 5 per cent. Hepatic resection of metastatic colorectal carcinoma can produce long‐term survival without prohibitive risk. These findings support an aggressive surgical approach for metastatic progression in the liver from colorectal carcinoma.

Original languageEnglish (US)
Pages (from-to)255-258
Number of pages4
JournalBritish Journal of Surgery
Volume81
Issue number2
DOIs
StatePublished - Jan 1 1994

Fingerprint

Neoplasm Metastasis
Liver
Disease Progression
Colorectal Neoplasms
Survival
Hepatectomy
Survival Rate
Morbidity
Mortality

ASJC Scopus subject areas

  • Surgery

Cite this

Resection of ‘recurrent’ colorectal metastases to the liver. / Que, Florencia; Nagorney, D. M.

In: British Journal of Surgery, Vol. 81, No. 2, 01.01.1994, p. 255-258.

Research output: Contribution to journalArticle

@article{e78282af737e4b88aac68f72caf564fe,
title = "Resection of ‘recurrent’ colorectal metastases to the liver",
abstract = "Hepatic resection is the only treatment for patients with colorectal cancer metastatic to the liver that has resulted in long‐term survival. This apparent efficacy of hepatectomy has prompted efforts to expand the surgical approach for disease progression within the liver. A review of personal experience and of the literature was performed in an attempt to define the role of surgery for disease progression. Twenty‐one patients who underwent hepatic resection between 1983 and 1991 for isolated disease progression in the liver were retrospectively reviewed. The median follow‐up of patients still alive was 1.7 years (range 4 months to 4.5 years). The median survival from the date of repeat hepatic resection was 3.4 years with an estimated actuarial survival rate of 43 per cent at 4 years. These patients experienced no significant morbidity and the mortality rate was 5 per cent. Hepatic resection of metastatic colorectal carcinoma can produce long‐term survival without prohibitive risk. These findings support an aggressive surgical approach for metastatic progression in the liver from colorectal carcinoma.",
author = "Florencia Que and Nagorney, {D. M.}",
year = "1994",
month = "1",
day = "1",
doi = "10.1002/bjs.1800810234",
language = "English (US)",
volume = "81",
pages = "255--258",
journal = "British Journal of Surgery",
issn = "0007-1323",
publisher = "John Wiley and Sons Ltd",
number = "2",

}

TY - JOUR

T1 - Resection of ‘recurrent’ colorectal metastases to the liver

AU - Que, Florencia

AU - Nagorney, D. M.

PY - 1994/1/1

Y1 - 1994/1/1

N2 - Hepatic resection is the only treatment for patients with colorectal cancer metastatic to the liver that has resulted in long‐term survival. This apparent efficacy of hepatectomy has prompted efforts to expand the surgical approach for disease progression within the liver. A review of personal experience and of the literature was performed in an attempt to define the role of surgery for disease progression. Twenty‐one patients who underwent hepatic resection between 1983 and 1991 for isolated disease progression in the liver were retrospectively reviewed. The median follow‐up of patients still alive was 1.7 years (range 4 months to 4.5 years). The median survival from the date of repeat hepatic resection was 3.4 years with an estimated actuarial survival rate of 43 per cent at 4 years. These patients experienced no significant morbidity and the mortality rate was 5 per cent. Hepatic resection of metastatic colorectal carcinoma can produce long‐term survival without prohibitive risk. These findings support an aggressive surgical approach for metastatic progression in the liver from colorectal carcinoma.

AB - Hepatic resection is the only treatment for patients with colorectal cancer metastatic to the liver that has resulted in long‐term survival. This apparent efficacy of hepatectomy has prompted efforts to expand the surgical approach for disease progression within the liver. A review of personal experience and of the literature was performed in an attempt to define the role of surgery for disease progression. Twenty‐one patients who underwent hepatic resection between 1983 and 1991 for isolated disease progression in the liver were retrospectively reviewed. The median follow‐up of patients still alive was 1.7 years (range 4 months to 4.5 years). The median survival from the date of repeat hepatic resection was 3.4 years with an estimated actuarial survival rate of 43 per cent at 4 years. These patients experienced no significant morbidity and the mortality rate was 5 per cent. Hepatic resection of metastatic colorectal carcinoma can produce long‐term survival without prohibitive risk. These findings support an aggressive surgical approach for metastatic progression in the liver from colorectal carcinoma.

UR - http://www.scopus.com/inward/record.url?scp=0028345790&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028345790&partnerID=8YFLogxK

U2 - 10.1002/bjs.1800810234

DO - 10.1002/bjs.1800810234

M3 - Article

C2 - 8156352

AN - SCOPUS:0028345790

VL - 81

SP - 255

EP - 258

JO - British Journal of Surgery

JF - British Journal of Surgery

SN - 0007-1323

IS - 2

ER -