Reproducibility of lung-to-head ratio ultrasound measurements in congenital diaphragmatic hernia

Victoria Arruga Novoa y Novoa, Laura F. Sutton, Allan E. Neis, Amber M. Marroquin, Tamara A. Freimund, Tracey M. Coleman, Kathleen A. Praska, Krystal L. Ruka, Vicki L. Warzala, Haleh Sangi-Haghpeykar, Rodrigo Ruano

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objectives—This study investigated the reproducibility of standardization of lungto- head ratio measurements in congenital diaphragmatic hernia (CDH) at our center among sonographers after we standardized the method. Methods—We reviewed ultrasound images of 12 fetuses with CDH at Mayo Clinic from 2010 to 2016. Nine operators (1 maternal-fetal medicine specialist with experience in measuring the lung-to-head ratio and 8 sonographers), who were blinded to previous findings, reviewed 33 selected images from 12 fetuses with left CDH. The method for lung-to-head ratio measurement was standardized before starting the measurements. The lung-to-head ratio was assessed by different methods to obtain the lung areas: anteroposterior, longest, and area tracing. We evaluated the correlation between operators using the intraclass correlation coefficient (ICC). We also compared agreement between the sonographers and a physician with experience in measuring the lung-to-head ratio using a Bland-Altman analysis. Results—The methods with the best interoperator reproducibility were the standardized anteroposterior lung-to-head ratio (ICC, 0.69) and the standardized lung-to-head ratio tracing (ICC, 0.65) compared to the longest lung-to-head ratio (ICC, 0.56). The standardized lung-to-head ratio tracing had the best agreement among sonographers and the physician (bias, 0.11; limits of agreement, 20.27 to10.49) than the anteroposterior lung-to-head ratio (bias, 0.35; limits of agreement, 20.13 to10.83) and the longest lung-to-head ratio (bias, 0.27; limits of agreement,20.35 to10.89). Conclusions—We demonstrated that the lung-to-head ratio tracing method has high interoperator reproducibility and the best agreement among the operators at our center. Further multicenter studies are necessary to confirm our results.

Original languageEnglish (US)
Pages (from-to)2037-2041
Number of pages5
JournalJournal of Ultrasound in Medicine
Volume37
Issue number8
DOIs
StatePublished - Jan 1 2018

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Head
Lung
Congenital Diaphragmatic Hernias
Fetus
Physicians
Multicenter Studies
Mothers
Medicine

Keywords

  • Congenital diaphragmatic hernia
  • Fetal lungs
  • Fetal therapy
  • Lungto- head ratio
  • Obstetrics (detailed fetal anatomy)
  • Obstetrics (second trimester)
  • Prenatal diagnosis
  • Pulmonary hypoplasia
  • Ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Novoa y Novoa, V. A., Sutton, L. F., Neis, A. E., Marroquin, A. M., Freimund, T. A., Coleman, T. M., ... Ruano, R. (2018). Reproducibility of lung-to-head ratio ultrasound measurements in congenital diaphragmatic hernia. Journal of Ultrasound in Medicine, 37(8), 2037-2041. https://doi.org/10.1002/jum.14557

Reproducibility of lung-to-head ratio ultrasound measurements in congenital diaphragmatic hernia. / Novoa y Novoa, Victoria Arruga; Sutton, Laura F.; Neis, Allan E.; Marroquin, Amber M.; Freimund, Tamara A.; Coleman, Tracey M.; Praska, Kathleen A.; Ruka, Krystal L.; Warzala, Vicki L.; Sangi-Haghpeykar, Haleh; Ruano, Rodrigo.

In: Journal of Ultrasound in Medicine, Vol. 37, No. 8, 01.01.2018, p. 2037-2041.

Research output: Contribution to journalArticle

Novoa y Novoa, VA, Sutton, LF, Neis, AE, Marroquin, AM, Freimund, TA, Coleman, TM, Praska, KA, Ruka, KL, Warzala, VL, Sangi-Haghpeykar, H & Ruano, R 2018, 'Reproducibility of lung-to-head ratio ultrasound measurements in congenital diaphragmatic hernia', Journal of Ultrasound in Medicine, vol. 37, no. 8, pp. 2037-2041. https://doi.org/10.1002/jum.14557
Novoa y Novoa VA, Sutton LF, Neis AE, Marroquin AM, Freimund TA, Coleman TM et al. Reproducibility of lung-to-head ratio ultrasound measurements in congenital diaphragmatic hernia. Journal of Ultrasound in Medicine. 2018 Jan 1;37(8):2037-2041. https://doi.org/10.1002/jum.14557
Novoa y Novoa, Victoria Arruga ; Sutton, Laura F. ; Neis, Allan E. ; Marroquin, Amber M. ; Freimund, Tamara A. ; Coleman, Tracey M. ; Praska, Kathleen A. ; Ruka, Krystal L. ; Warzala, Vicki L. ; Sangi-Haghpeykar, Haleh ; Ruano, Rodrigo. / Reproducibility of lung-to-head ratio ultrasound measurements in congenital diaphragmatic hernia. In: Journal of Ultrasound in Medicine. 2018 ; Vol. 37, No. 8. pp. 2037-2041.
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abstract = "Objectives—This study investigated the reproducibility of standardization of lungto- head ratio measurements in congenital diaphragmatic hernia (CDH) at our center among sonographers after we standardized the method. Methods—We reviewed ultrasound images of 12 fetuses with CDH at Mayo Clinic from 2010 to 2016. Nine operators (1 maternal-fetal medicine specialist with experience in measuring the lung-to-head ratio and 8 sonographers), who were blinded to previous findings, reviewed 33 selected images from 12 fetuses with left CDH. The method for lung-to-head ratio measurement was standardized before starting the measurements. The lung-to-head ratio was assessed by different methods to obtain the lung areas: anteroposterior, longest, and area tracing. We evaluated the correlation between operators using the intraclass correlation coefficient (ICC). We also compared agreement between the sonographers and a physician with experience in measuring the lung-to-head ratio using a Bland-Altman analysis. Results—The methods with the best interoperator reproducibility were the standardized anteroposterior lung-to-head ratio (ICC, 0.69) and the standardized lung-to-head ratio tracing (ICC, 0.65) compared to the longest lung-to-head ratio (ICC, 0.56). The standardized lung-to-head ratio tracing had the best agreement among sonographers and the physician (bias, 0.11; limits of agreement, 20.27 to10.49) than the anteroposterior lung-to-head ratio (bias, 0.35; limits of agreement, 20.13 to10.83) and the longest lung-to-head ratio (bias, 0.27; limits of agreement,20.35 to10.89). Conclusions—We demonstrated that the lung-to-head ratio tracing method has high interoperator reproducibility and the best agreement among the operators at our center. Further multicenter studies are necessary to confirm our results.",
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AU - Freimund, Tamara A.

AU - Coleman, Tracey M.

AU - Praska, Kathleen A.

AU - Ruka, Krystal L.

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KW - Pulmonary hypoplasia

KW - Ultrasound

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