Reproducibility of linear array for human papillomavirus genotyping

Jill Koshiol, S. Terence Dunn, Joan L. Walker, Rosemary E. Zuna, Mark Schiffman, Mark E. Sherman, Michael A. Gold, Richard A. Allen, Roy Zhang, Sophia S. Wang, Nicolas Wentzensen

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We conducted a Linear Array test/retest analysis using cytologic specimens from 198 women. A total of 67.2% of samples had the same human papillomavirus (HPV) types detected in both tests (type-specific positive agreement was 83.3% overall [Kappa= 0.9] and 86.8% for carcinogenic types [Kappa=0.92]). Discordance was highest with a low hybridization signal strength. Overall, Linear Array was highly reproducible.

Original languageEnglish (US)
Pages (from-to)625-628
Number of pages4
JournalJournal of clinical microbiology
Volume51
Issue number2
DOIs
StatePublished - Feb 2013

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Koshiol, J., Terence Dunn, S., Walker, J. L., Zuna, R. E., Schiffman, M., Sherman, M. E., Gold, M. A., Allen, R. A., Zhang, R., Wang, S. S., & Wentzensen, N. (2013). Reproducibility of linear array for human papillomavirus genotyping. Journal of clinical microbiology, 51(2), 625-628. https://doi.org/10.1128/JCM.03036-12