Reproducibility of linear array for human papillomavirus genotyping

Jill Koshiol; S. Terence Dunn; Joan L. Walker; Rosemary E. Zuna; Mark Schiffman; Mark E. Sherman; Michael A. Gold; Richard A. Allen; Roy Zhang; Sophia S. Wang; Nicolas Wentzensen

doi:10.1128/JCM.03036-12

Reproducibility of linear array for human papillomavirus genotyping

Jill Koshiol, S. Terence Dunn, Joan L. Walker, Rosemary E. Zuna, Mark Schiffman, Mark E. Sherman, Michael A. Gold, Richard A. Allen, Roy Zhang, Sophia S. Wang, Nicolas Wentzensen

Quantitative Health Sciences

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We conducted a Linear Array test/retest analysis using cytologic specimens from 198 women. A total of 67.2% of samples had the same human papillomavirus (HPV) types detected in both tests (type-specific positive agreement was 83.3% overall [Kappa= 0.9] and 86.8% for carcinogenic types [Kappa=0.92]). Discordance was highest with a low hybridization signal strength. Overall, Linear Array was highly reproducible.

Original language	English (US)
Pages (from-to)	625-628
Number of pages	4
Journal	Journal of clinical microbiology
Volume	51
Issue number	2
DOIs	https://doi.org/10.1128/JCM.03036-12
State	Published - Feb 2013

ASJC Scopus subject areas

Microbiology (medical)

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title = "Reproducibility of linear array for human papillomavirus genotyping",

abstract = "We conducted a Linear Array test/retest analysis using cytologic specimens from 198 women. A total of 67.2% of samples had the same human papillomavirus (HPV) types detected in both tests (type-specific positive agreement was 83.3% overall [Kappa= 0.9] and 86.8% for carcinogenic types [Kappa=0.92]). Discordance was highest with a low hybridization signal strength. Overall, Linear Array was highly reproducible.",

author = "Jill Koshiol and {Terence Dunn}, S. and Walker, {Joan L.} and Zuna, {Rosemary E.} and Mark Schiffman and Sherman, {Mark E.} and Gold, {Michael A.} and Allen, {Richard A.} and Roy Zhang and Wang, {Sophia S.} and Nicolas Wentzensen",

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AU - Terence Dunn, S.

AU - Walker, Joan L.

AU - Zuna, Rosemary E.

AU - Schiffman, Mark

AU - Sherman, Mark E.

AU - Gold, Michael A.

AU - Allen, Richard A.

AU - Zhang, Roy

AU - Wang, Sophia S.

AU - Wentzensen, Nicolas

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Reproducibility of linear array for human papillomavirus genotyping

Abstract

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