Renal failure limiting antihypertensive therapy as an indication for renal revascularization. A case report

Stephen C Textor, A. C. Novick, D. R. Steinmuller, S. B. Streem

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Although surgical repair of renal artery stenosis occasionally improves renal function, it is not yet known when revascularization is indicated for that reason. We report the results observed in a patient with renovascular hypertension and additional stenosis in the contralateral kidney whose renal function deteriorated on repeated occasions during antihypertensive therapy. Renal hemodynamic studies during sodiumnitroprusside infusion showed severely impaired autoregulation of blood flow, and glomerular filtration rate was corrected after revascularization of the contralateral kidney alone. After surgery, normal BPs were tolerated without loss of function. These findings demonstrate a specific clinical indication for renal revascularization to preserve kidney function.

Original languageEnglish (US)
Pages (from-to)2208-2211
Number of pages4
JournalArchives of Internal Medicine
Volume143
Issue number11
DOIs
StatePublished - 1983
Externally publishedYes

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Antihypertensive Agents
Renal Insufficiency
Kidney
Therapeutics
Renovascular Hypertension
Renal Artery Obstruction
Glomerular Filtration Rate
Pathologic Constriction
Homeostasis
Hemodynamics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Renal failure limiting antihypertensive therapy as an indication for renal revascularization. A case report. / Textor, Stephen C; Novick, A. C.; Steinmuller, D. R.; Streem, S. B.

In: Archives of Internal Medicine, Vol. 143, No. 11, 1983, p. 2208-2211.

Research output: Contribution to journalArticle

Textor, Stephen C ; Novick, A. C. ; Steinmuller, D. R. ; Streem, S. B. / Renal failure limiting antihypertensive therapy as an indication for renal revascularization. A case report. In: Archives of Internal Medicine. 1983 ; Vol. 143, No. 11. pp. 2208-2211.
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