Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease

Elizabeth C. Lorenz, Sanjeev Sethi, Tanya L. Poshusta, Marina Ramirez-Alvarado, Shaji Kumar, Donna J. Lager, Fernando C. Fervenza, Nelson Leung

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Renal dysfunction commonly occurs in multiple myeloma (MM) and is caused by deposition of abnormal light chain within various compartments of the kidney. Renal pathologic findings are diverse and include cast nephropathy (CN), amyloidosis and light-chain deposition disease (LCDD). We report a case of renal failure in a patient with MM caused by concurrent CN, amyloidosis and LCDD which has not been previously described.

Original languageEnglish (US)
Pages (from-to)1340-1343
Number of pages4
JournalNephrology Dialysis Transplantation
Volume25
Issue number4
DOIs
StatePublished - Apr 1 2010

Keywords

  • Amyloidosis
  • Light chain
  • Myeloma
  • Nephropathy

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

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