Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease

Elizabeth C. Lorenz; Sanjeev Sethi; Tanya L. Poshusta; Marina Ramirez-Alvarado; Shaji Kumar; Donna J. Lager; Fernando C. Fervenza; Nelson Leung

doi:10.1093/ndt/gfp735

Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease

Elizabeth C. Lorenz, Sanjeev Sethi, Tanya L. Poshusta, Marina Ramirez-Alvarado, Shaji Kumar, Donna J. Lager, Fernando C. Fervenza, Nelson Leung

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Renal dysfunction commonly occurs in multiple myeloma (MM) and is caused by deposition of abnormal light chain within various compartments of the kidney. Renal pathologic findings are diverse and include cast nephropathy (CN), amyloidosis and light-chain deposition disease (LCDD). We report a case of renal failure in a patient with MM caused by concurrent CN, amyloidosis and LCDD which has not been previously described.

Original language	English (US)
Pages (from-to)	1340-1343
Number of pages	4
Journal	Nephrology Dialysis Transplantation
Volume	25
Issue number	4
DOIs	https://doi.org/10.1093/ndt/gfp735
State	Published - Apr 2010

Keywords

Amyloidosis
Light chain
Myeloma
Nephropathy

ASJC Scopus subject areas

Nephrology
Transplantation

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10.1093/ndt/gfp735

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abstract = "Renal dysfunction commonly occurs in multiple myeloma (MM) and is caused by deposition of abnormal light chain within various compartments of the kidney. Renal pathologic findings are diverse and include cast nephropathy (CN), amyloidosis and light-chain deposition disease (LCDD). We report a case of renal failure in a patient with MM caused by concurrent CN, amyloidosis and LCDD which has not been previously described.",

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AU - Ramirez-Alvarado, Marina

AU - Kumar, Shaji

AU - Lager, Donna J.

AU - Fervenza, Fernando C.

AU - Leung, Nelson

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AB - Renal dysfunction commonly occurs in multiple myeloma (MM) and is caused by deposition of abnormal light chain within various compartments of the kidney. Renal pathologic findings are diverse and include cast nephropathy (CN), amyloidosis and light-chain deposition disease (LCDD). We report a case of renal failure in a patient with MM caused by concurrent CN, amyloidosis and LCDD which has not been previously described.

KW - Amyloidosis

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KW - Myeloma

KW - Nephropathy

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Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease

Abstract

Keywords

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