Renal Blood Flow during Nadolol Administration

To the Editor: Textor et al.¹ are to be commended for their observation that renal perfusion was preserved during beta blockade with nadolol in patients with hypertension, as well as their ingenious use of the ratio of renal blood flow to cardiac output as an index of renal-perfusion redistribution (September 2 issue). We too have noted the preservation of renal blood flow during antihypertensive therapy with nadolol,² as opposed to our findings of diminished renal blood flow during administration of propranolol for treatment of hypertension.^3,4 Thus, different beta blockers may have different effects on the renal circulation. However, I believe.