Renal artery intervention in pediatric and adolescent patients: A 20-year experience

Ying Huang, Audra A. Duncan, Michael A. McKusick, Dawn S. Milliner, Thomas C. Bower, Manju Kalra, Peter Gloviczki, Tanya L. Hoskin

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Between 1986 and 2005, 22 patients (mean age, 14.7 years; range, 3-21) with renal hypertension underwent renal artery revascularization for 28 lesions, 23 with open repair (OR) and 5 with percutaneous transluminal renal angioplasty (PTRA). Thirty-day morbidity was 17% (4/23). Hypertension was cured in 13 (57%), improved in 8 (38%), and unchanged in 1 (5%). Renal function worsened in 1. At a mean follow-up of 4.9 years, 1-year patency rate was 94% and maintained for 5 years. Hypertension at 1 year was cured in 6 of 14 patients (43%; OR, 4; PTRA, 2) and improved in 8 (57%; OR, 7; PTRA, 1); hypertension at 5 years was cured in 50% and improved in 50%. Renal function remained unchanged in all patients who were followed. The authors conclude that both OR and PTRA benefit pediatric patients. PTRA for selected patients may be promising as a first line treatment or as a bridge to definitive OR in children with small arteries.

Original languageEnglish (US)
Pages (from-to)490-499
Number of pages10
JournalVascular and Endovascular Surgery
Volume41
Issue number6
DOIs
StatePublished - Dec 1 2008

Keywords

  • Adolescent
  • Hypertension
  • Intervention
  • Pediatric
  • Renal artery disease

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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    Huang, Y., Duncan, A. A., McKusick, M. A., Milliner, D. S., Bower, T. C., Kalra, M., Gloviczki, P., & Hoskin, T. L. (2008). Renal artery intervention in pediatric and adolescent patients: A 20-year experience. Vascular and Endovascular Surgery, 41(6), 490-499. https://doi.org/10.1177/1538574407307944