Relevant contact sensitivities in patients with the diagnosis of oral lichen planus

James A. Yiannias, Rokea A. El-Azhary, Jennifer H. Hand, Soheil Y. Pakzad, Roy S. Rogers

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Background: The concept of contact allergy aggravating or inducing oral lichenoid mucositis diagnosed as oral liche planus (OLP) is well recognized but somewhat controversial. Objective: We sought to identify clinically relevant contact allergens that may be important in the management of patients with OLP. Methods: We retrospectively reviewed patients with OLP who had patch tests performed at Mayo Clinic Rochester and Mayo Clinic Scottsdale from 1994 to 1997 and 1988 to 1997, respectively. Results: Patch tests were performed on 46 patients with a clinical and histopathologic diagnosis of OLP. Of these, 25 (54%) had positive patch test results. Eighteen (72%) of the patients with positive results had clinically relevant reactions. Of the patients with positive metal reactions, 5 had improvement after removal of the metal prosthesis or restoration. Six others noted that their most troublesome areas were adjacent to metal dental restorations. Six patients with reactions to flavorings and one patient with an acrylate dental retainer sensitivity had improvement after avoiding these allergens. Conclusion: Our findings support the concept that contact allergy to metals, flavorings, and plastics can be important in the pathogenesis and management of patients with oral lichenoid mucositis diagnosed as OLP.

Original languageEnglish (US)
Pages (from-to)177-182
Number of pages6
JournalJournal of the American Academy of Dermatology
Volume42
Issue number2 I
StatePublished - Feb 2000

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Oral Lichen Planus
Contact Dermatitis
Patch Tests
Metals
Stomatitis
Allergens
Hypersensitivity
Dentin Sensitivity
Oral Diagnosis
Plastics
Prostheses and Implants
Tooth

ASJC Scopus subject areas

  • Dermatology

Cite this

Yiannias, J. A., El-Azhary, R. A., Hand, J. H., Pakzad, S. Y., & Rogers, R. S. (2000). Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. Journal of the American Academy of Dermatology, 42(2 I), 177-182.

Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. / Yiannias, James A.; El-Azhary, Rokea A.; Hand, Jennifer H.; Pakzad, Soheil Y.; Rogers, Roy S.

In: Journal of the American Academy of Dermatology, Vol. 42, No. 2 I, 02.2000, p. 177-182.

Research output: Contribution to journalArticle

Yiannias, JA, El-Azhary, RA, Hand, JH, Pakzad, SY & Rogers, RS 2000, 'Relevant contact sensitivities in patients with the diagnosis of oral lichen planus', Journal of the American Academy of Dermatology, vol. 42, no. 2 I, pp. 177-182.
Yiannias JA, El-Azhary RA, Hand JH, Pakzad SY, Rogers RS. Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. Journal of the American Academy of Dermatology. 2000 Feb;42(2 I):177-182.
Yiannias, James A. ; El-Azhary, Rokea A. ; Hand, Jennifer H. ; Pakzad, Soheil Y. ; Rogers, Roy S. / Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. In: Journal of the American Academy of Dermatology. 2000 ; Vol. 42, No. 2 I. pp. 177-182.
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