TY - JOUR
T1 - Relative contributions of incidence and survival to increasing prevalence of adult-onset diabetes mellitus
T2 - A population-based study
AU - Leibson, Cynthia L.
AU - O'Brien, Peter C.
AU - Atkinson, Elizabeth
AU - Palumbo, Pasquale J.
AU - Melton, L. Joseph
N1 - Funding Information:
Supported by National Institutes of Health research grants AGO8729 and AR30582. Portions of this work were presented and published in abstract form for the 48th Annual Scientific Meeting of the Gerontological Society of America (The Gerontologist 1995;35:319A). The authors thank Rita Black and Jo Johnson for their superb data collection and Tischa Agnessi for her expert data analysis.
PY - 1997/7/1
Y1 - 1997/7/1
N2 - This population-based retrospective study investigates temporal trends in adult-onset diabetes mellitus prevalence, incidence, and survival. The complete community-based medical records, including laboratory results, of all Rochester, Minnesota, residents with a clinical diagnosis of diabetes or diabetes-like condition were reviewed to identify incidence cases aged 30 years or more from 1945 to 1989 (n = 1,847) and prevalence cases aged 45 years or more on January 1, 1970 (n = 465), January 1, 1980 (n = 689), or January 1, 1990 (n = 973). Glucose values and case definitions were standardized throughout. Observed 10-year survival for 1970 and 1980 prevalence cases was compared with that expected for Minnesota white populations in 1970 and 1980, respectively. Age-adjusted prevalence rose 65% for men and 37% for women between 1970 and 1990. There were marked differences among prevalence groups in treatment type, the proportion diagnosed using glucose tolerance tests, and the proportion categorized as obese. Relative survival for 1980 prevalence cases was not greater than that for 1970 prevalence cases. Age-adjusted incidence rates rose 47% for men and 26% for women between 1960 and 1965 and 1985 and 1989. These findings emphasize the need for heightened surveillance and intervention to reduce the burden of illness from adult-onset diabetes mellitus in the population.
AB - This population-based retrospective study investigates temporal trends in adult-onset diabetes mellitus prevalence, incidence, and survival. The complete community-based medical records, including laboratory results, of all Rochester, Minnesota, residents with a clinical diagnosis of diabetes or diabetes-like condition were reviewed to identify incidence cases aged 30 years or more from 1945 to 1989 (n = 1,847) and prevalence cases aged 45 years or more on January 1, 1970 (n = 465), January 1, 1980 (n = 689), or January 1, 1990 (n = 973). Glucose values and case definitions were standardized throughout. Observed 10-year survival for 1970 and 1980 prevalence cases was compared with that expected for Minnesota white populations in 1970 and 1980, respectively. Age-adjusted prevalence rose 65% for men and 37% for women between 1970 and 1990. There were marked differences among prevalence groups in treatment type, the proportion diagnosed using glucose tolerance tests, and the proportion categorized as obese. Relative survival for 1980 prevalence cases was not greater than that for 1970 prevalence cases. Age-adjusted incidence rates rose 47% for men and 26% for women between 1960 and 1965 and 1985 and 1989. These findings emphasize the need for heightened surveillance and intervention to reduce the burden of illness from adult-onset diabetes mellitus in the population.
KW - Diabetes mellitus
KW - Incidence
KW - Mortality
KW - Non-insulin- dependent
KW - Obesity
KW - Prevalence
UR - http://www.scopus.com/inward/record.url?scp=0030846443&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030846443&partnerID=8YFLogxK
U2 - 10.1093/oxfordjournals.aje.a009187
DO - 10.1093/oxfordjournals.aje.a009187
M3 - Article
C2 - 9215219
AN - SCOPUS:0030846443
VL - 146
SP - 12
EP - 22
JO - American Journal of Epidemiology
JF - American Journal of Epidemiology
SN - 0002-9262
IS - 1
ER -