Abstract
Background: Hypertriglyceridemia has been associated with adverse outcomes in patients receiving intravenous fat emulsions (IVFEs), but little is known about its prevalence and causes. Materials and Methods: The study investigated whether a relationship exists between body mass index (BMI) and triglyceride tolerance in parenterally fed patients. We conducted a retrospective analysis of 287 adults receiving parenteral nutrition to determine whether patients with very low BMI (VLBMI, 2) tolerate IVFEs better than do patients with low BMI (LBMI, 16-18.4 kg/m2), normal-weight patients (NBMI, 18.5-24.9 kg/m2), and overweight/obese patients (HBMI, ‰25 kg/m2). Results: The median triglyceride concentration during IVFE was significantly lower in VLBMI patients at 107 mg/dL compared with 124 mg/dL in non-VLBMI patients (P =.016), despite higher lipid infusion rates in the VLBMI group. There was a significant association between triglycerides and BMI in the aggregate cohort (R = 0.2375, P
Original language | English (US) |
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Pages (from-to) | 922-928 |
Number of pages | 7 |
Journal | Journal of Parenteral and Enteral Nutrition |
Volume | 39 |
Issue number | 8 |
DOIs | |
State | Published - Nov 1 2015 |
Keywords
- adult
- life cycle
- lipids
- nutrition
- obesity
- parenteral nutrition
- research and diseases
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics