Relation of Postdischarge Care Fragmentation and Outcomes in Transcatheter Aortic Valve Implantation from the STS/ACC TVT Registry

Alice Wang, Zhuokai Li, Jennifer A. Rymer, Andrzej S. Kosinski, Babatunde Yerokun, Morgan L. Cox, Brian C. Gulack, Matthew W. Sherwood, Renato D. Lopes, Taku Inohara, Vinod Thourani, Ajay J. Kirtane, David Holmes, G. Chad Hughes, J. Kevin Harrison, Peter K. Smith, Sreekanth Vemulapalli

Research output: Contribution to journalArticle

Abstract

Fragmented care following elective surgery has been associated with poor outcomes. The association between fragmented care and outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) is unknown. We examined patients who underwent TAVI from 2011 to 2015 at 374 sites in the STS/ACC TVT Registry, linked to Center for Medicare and Medicaid Services claims data. Fragmented care was defined as at least one readmission to a site other than the implanting TAVI center within 90 days after discharge, whereas continuous care was defined as readmission to the same implanting center. We compared adjusted 1-year outcomes, including stroke, bleeding, heart failure, mortality, and all-cause readmission in patients who received fragmented versus continuous care. Among 8,927 patients who received a TAVI between 2011 and 2015, 27.4% were readmitted within 90 days of discharge. Most patients received fragmented care (57.0%). Compared with the continuous care group, the fragmented care group was more likely to have severe chronic lung disease, cerebrovascular disease, and heart failure. States that had lower TAVI volume per Center for Medicare and Medicaid Services population had greater fragmentation. Patients living > 30 minutes from their TAVI center had an increased risk of fragmented care 1.07 (confidence interval [CI] 1.06 to 1.09, p < 0.001). After adjustment for comorbidities and procedural complications, fragmented care was associated with increased 1-year mortality (hazards ratio 1.18, CI 1.04 to 1.35, p = 0.010) and all-cause readmission (hazards ratio 1.08, CI 1.00 to 1.16, p = 0.051. In conclusion, fragmented readmission following TAVI is common, and is associated with increased 1-year mortality and readmission. Efforts to improve coordination of care may improve these outcomes and optimize long-term benefits yielded from TAVI.

Original languageEnglish (US)
Pages (from-to)912-919
Number of pages8
JournalAmerican Journal of Cardiology
Volume124
Issue number6
DOIs
StatePublished - Sep 15 2019

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Registries
Centers for Medicare and Medicaid Services (U.S.)
Confidence Intervals
Mortality
Heart Failure
Cerebrovascular Disorders
Patient Readmission
Transcatheter Aortic Valve Replacement
Lung Diseases
Comorbidity
Chronic Disease
Stroke
Hemorrhage
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Relation of Postdischarge Care Fragmentation and Outcomes in Transcatheter Aortic Valve Implantation from the STS/ACC TVT Registry. / Wang, Alice; Li, Zhuokai; Rymer, Jennifer A.; Kosinski, Andrzej S.; Yerokun, Babatunde; Cox, Morgan L.; Gulack, Brian C.; Sherwood, Matthew W.; Lopes, Renato D.; Inohara, Taku; Thourani, Vinod; Kirtane, Ajay J.; Holmes, David; Hughes, G. Chad; Harrison, J. Kevin; Smith, Peter K.; Vemulapalli, Sreekanth.

In: American Journal of Cardiology, Vol. 124, No. 6, 15.09.2019, p. 912-919.

Research output: Contribution to journalArticle

Wang, A, Li, Z, Rymer, JA, Kosinski, AS, Yerokun, B, Cox, ML, Gulack, BC, Sherwood, MW, Lopes, RD, Inohara, T, Thourani, V, Kirtane, AJ, Holmes, D, Hughes, GC, Harrison, JK, Smith, PK & Vemulapalli, S 2019, 'Relation of Postdischarge Care Fragmentation and Outcomes in Transcatheter Aortic Valve Implantation from the STS/ACC TVT Registry', American Journal of Cardiology, vol. 124, no. 6, pp. 912-919. https://doi.org/10.1016/j.amjcard.2019.06.005
Wang, Alice ; Li, Zhuokai ; Rymer, Jennifer A. ; Kosinski, Andrzej S. ; Yerokun, Babatunde ; Cox, Morgan L. ; Gulack, Brian C. ; Sherwood, Matthew W. ; Lopes, Renato D. ; Inohara, Taku ; Thourani, Vinod ; Kirtane, Ajay J. ; Holmes, David ; Hughes, G. Chad ; Harrison, J. Kevin ; Smith, Peter K. ; Vemulapalli, Sreekanth. / Relation of Postdischarge Care Fragmentation and Outcomes in Transcatheter Aortic Valve Implantation from the STS/ACC TVT Registry. In: American Journal of Cardiology. 2019 ; Vol. 124, No. 6. pp. 912-919.
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abstract = "Fragmented care following elective surgery has been associated with poor outcomes. The association between fragmented care and outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) is unknown. We examined patients who underwent TAVI from 2011 to 2015 at 374 sites in the STS/ACC TVT Registry, linked to Center for Medicare and Medicaid Services claims data. Fragmented care was defined as at least one readmission to a site other than the implanting TAVI center within 90 days after discharge, whereas continuous care was defined as readmission to the same implanting center. We compared adjusted 1-year outcomes, including stroke, bleeding, heart failure, mortality, and all-cause readmission in patients who received fragmented versus continuous care. Among 8,927 patients who received a TAVI between 2011 and 2015, 27.4{\%} were readmitted within 90 days of discharge. Most patients received fragmented care (57.0{\%}). Compared with the continuous care group, the fragmented care group was more likely to have severe chronic lung disease, cerebrovascular disease, and heart failure. States that had lower TAVI volume per Center for Medicare and Medicaid Services population had greater fragmentation. Patients living > 30 minutes from their TAVI center had an increased risk of fragmented care 1.07 (confidence interval [CI] 1.06 to 1.09, p < 0.001). After adjustment for comorbidities and procedural complications, fragmented care was associated with increased 1-year mortality (hazards ratio 1.18, CI 1.04 to 1.35, p = 0.010) and all-cause readmission (hazards ratio 1.08, CI 1.00 to 1.16, p = 0.051. In conclusion, fragmented readmission following TAVI is common, and is associated with increased 1-year mortality and readmission. Efforts to improve coordination of care may improve these outcomes and optimize long-term benefits yielded from TAVI.",
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AU - Kosinski, Andrzej S.

AU - Yerokun, Babatunde

AU - Cox, Morgan L.

AU - Gulack, Brian C.

AU - Sherwood, Matthew W.

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AU - Thourani, Vinod

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