Relapsing polychondritis

Harvinder S. Luthra

doi:10.1007/978-1-84800-934-9_32

Relapsing polychondritis

Harvinder S. Luthra

Rheumatology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Relapsing polychondritis (RP) is a multisystem inflammatory disease of unknown etiology in which the cartilaginous structures of the ears, nose, trachea, and joints are the main sites of damage. A variety of other organs and tissues, including the eyes, heart, and blood vessels, can also be affected by RP. Clues from human and animal studies suggest that cartilage components may be the antigens driving the immune response, leading to damage from the resulting inflammation. First described by Jaksch-Wartenhorst (1923), more than 500 patients with RP have been reported in the medical literature. RP has a worldwide distribution. Some RP cases are associated with other conditions, particularly myelodysplastic syndromes and connective tissue disorders such as rheumatoid arthritis or systemic lupus erythematosus.

Original language	English (US)
Title of host publication	A Clinician's Pearls and Myths in Rheumatology
Publisher	Springer London
Pages	335-339
Number of pages	5
ISBN (Print)	9781848009332
DOIs	https://doi.org/10.1007/978-1-84800-934-9_32
State	Published - 2009

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-84800-934-9_32

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title = "Relapsing polychondritis",

abstract = "Relapsing polychondritis (RP) is a multisystem inflammatory disease of unknown etiology in which the cartilaginous structures of the ears, nose, trachea, and joints are the main sites of damage. A variety of other organs and tissues, including the eyes, heart, and blood vessels, can also be affected by RP. Clues from human and animal studies suggest that cartilage components may be the antigens driving the immune response, leading to damage from the resulting inflammation. First described by Jaksch-Wartenhorst (1923), more than 500 patients with RP have been reported in the medical literature. RP has a worldwide distribution. Some RP cases are associated with other conditions, particularly myelodysplastic syndromes and connective tissue disorders such as rheumatoid arthritis or systemic lupus erythematosus.",

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N2 - Relapsing polychondritis (RP) is a multisystem inflammatory disease of unknown etiology in which the cartilaginous structures of the ears, nose, trachea, and joints are the main sites of damage. A variety of other organs and tissues, including the eyes, heart, and blood vessels, can also be affected by RP. Clues from human and animal studies suggest that cartilage components may be the antigens driving the immune response, leading to damage from the resulting inflammation. First described by Jaksch-Wartenhorst (1923), more than 500 patients with RP have been reported in the medical literature. RP has a worldwide distribution. Some RP cases are associated with other conditions, particularly myelodysplastic syndromes and connective tissue disorders such as rheumatoid arthritis or systemic lupus erythematosus.

AB - Relapsing polychondritis (RP) is a multisystem inflammatory disease of unknown etiology in which the cartilaginous structures of the ears, nose, trachea, and joints are the main sites of damage. A variety of other organs and tissues, including the eyes, heart, and blood vessels, can also be affected by RP. Clues from human and animal studies suggest that cartilage components may be the antigens driving the immune response, leading to damage from the resulting inflammation. First described by Jaksch-Wartenhorst (1923), more than 500 patients with RP have been reported in the medical literature. RP has a worldwide distribution. Some RP cases are associated with other conditions, particularly myelodysplastic syndromes and connective tissue disorders such as rheumatoid arthritis or systemic lupus erythematosus.

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DO - 10.1007/978-1-84800-934-9_32

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SP - 335

EP - 339

BT - A Clinician's Pearls and Myths in Rheumatology

PB - Springer London

ER -

Relapsing polychondritis

Abstract

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