Relapsing polychondritis

Harvinder S. Luthra

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Relapsing polychondritis is a recurring inflammatory disorder of unknown etiology causing inflammatory reactions in the cartilaginous structures of the nose, ears, trachea, and the joints. It is considered an auto-immune disorder. It was first described by Jaksch-Wartenhorst (1), in a patient with systemic illness characterized by external ear swelling, collapse of the nasal bridge, fever, and arthritis. Pearson and colleagues (2) first coined the term relapsing polychondritis (RP), and described, in detail, the clinical features of several of their own patients along with those in the literature. Since then, this disorder has been described worldwide and occurs in all age groups, although it peaks in the fifth decade. Over 30% of patients have an associated disorder, usually autoimmune or hematologic. These include systemic vasculitis syndromes, systemic lupus erythematosus (SLE), Sjögren's syndrome, overlap connective tissue disorders, rheumatoid arthritis (RA), spondyloarthropathies, dysmyelopoietic syndromes, Hodgkin's disease, diabetes mellitis, and psoriasis vulgaris (3). It is a rare disease occuring in 3.5 person's per million (Michet, personal communication). The 5-year survival is decreased to approximately 74%. The male:female ratio is equal (4).

Original languageEnglish (US)
Title of host publicationPrimer on the Rheumatic Diseases: Thirteenth Edition
PublisherSpringer New York
Pages451-454
Number of pages4
ISBN (Print)9780387356648
DOIs
StatePublished - 2008

Fingerprint

Relapsing Polychondritis
Nose
Structure Collapse
External Ear
Spondylarthropathies
Systemic Vasculitis
Myelodysplastic Syndromes
Immune System Diseases
Rare Diseases
Trachea
Hodgkin Disease
Psoriasis
Systemic Lupus Erythematosus
Connective Tissue
Arthritis
Ear
Rheumatoid Arthritis
Fever
Age Groups
Joints

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Luthra, H. S. (2008). Relapsing polychondritis. In Primer on the Rheumatic Diseases: Thirteenth Edition (pp. 451-454). Springer New York. https://doi.org/10.1007/978-0-387-68566-3_22

Relapsing polychondritis. / Luthra, Harvinder S.

Primer on the Rheumatic Diseases: Thirteenth Edition. Springer New York, 2008. p. 451-454.

Research output: Chapter in Book/Report/Conference proceedingChapter

Luthra, HS 2008, Relapsing polychondritis. in Primer on the Rheumatic Diseases: Thirteenth Edition. Springer New York, pp. 451-454. https://doi.org/10.1007/978-0-387-68566-3_22
Luthra HS. Relapsing polychondritis. In Primer on the Rheumatic Diseases: Thirteenth Edition. Springer New York. 2008. p. 451-454 https://doi.org/10.1007/978-0-387-68566-3_22
Luthra, Harvinder S. / Relapsing polychondritis. Primer on the Rheumatic Diseases: Thirteenth Edition. Springer New York, 2008. pp. 451-454
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