Relapsing inappropriate antidiuretic hormone secretion in an anti-aquaporin-4 antibody positive paediatric patient

Ruzica Kravljanac, Vanja Martinović, Irena Dujmović, Milena Djurić, Miloš Kuzmanović, Brian G Weinshenker, Jelena Drulović

Research output: Contribution to journalArticle

3 Scopus citations


Paediatric patients with the syndrome of an inappropriate antidiuretic hormone secretion (SIADH), as a manifestation of inflammatory demyelinating disorders of the central nervous system, have been rarely described until now, in only a few cases of neuromyelitis optica spectrum disorders (NMOSDs). We present a case of relapsing SIADH associated with NMOSD, in an anti-aquaporin-4 antibody positive 14-year-old girl, who is, to our best knowledge, the first reported paediatric patient with relapsing SIADH and NMOSD. Additionally, our case further supports the notion that paediatric encephalomyelitis associated with SIADH should suggest the diagnosis of NMOSD.

Original languageEnglish (US)
Pages (from-to)1404-1406
Number of pages3
JournalMultiple sclerosis (Houndmills, Basingstoke, England)
Issue number10
StatePublished - Sep 1 2014



  • anti-aquaporin-4 antibody
  • MRI
  • Neuromyelitis optica
  • paediatric patient

ASJC Scopus subject areas

  • Medicine(all)

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