Relapsing fevers and lymphadenopathy in a young woman

Raghuwansh P. Sah, Michael Wilson, Justin Seningen, Anjali Bhagra

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 23-year-old woman presented to the emergency department with severe occipital headache, nausea and fever. She was treated with intravenous antibiotics for suspected meningitis. After a brief period of response, her symptoms relapsed and remained refractory despite continuing intravenous antibiotics for 10 days leading to referral to our centre. Physical examination was significant for tender right cervical lymph node. Initial tests included pancytopenia, elevated C reactive protein, lactate dehydrogenase and unremarkable cerebrospinal fluid. Extensive infectious and rheumatology work-up was negative. Massive posterior cervical, axillary and inguinal lymphadenopathy was revealed on imaging. Excisional biopsy of the deep cervical lymph node showed histiocytic necrotising lymphadenitis suggesting a diagnosis of Kikuchi disease. Her course was complicated by acute renal failure. Her symptoms resolved in about a week with supportive treatment along with improvement in pancytopenia and renal function. She had two additional self-limited recurrences in the next 3 months and remains symptom free thereafter.

Original languageEnglish (US)
Article number200237
JournalBMJ Case Reports
DOIs
StatePublished - Jul 13 2013

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Histiocytic Necrotizing Lymphadenitis
Relapsing Fever
Pancytopenia
Lymph Nodes
Anti-Bacterial Agents
Groin
Rheumatology
L-Lactate Dehydrogenase
Meningitis
Acute Kidney Injury
C-Reactive Protein
Nausea
Physical Examination
Headache
Cerebrospinal Fluid
Hospital Emergency Service
Fever
Referral and Consultation
Kidney
Biopsy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Relapsing fevers and lymphadenopathy in a young woman. / Sah, Raghuwansh P.; Wilson, Michael; Seningen, Justin; Bhagra, Anjali.

In: BMJ Case Reports, 13.07.2013.

Research output: Contribution to journalArticle

Sah, Raghuwansh P. ; Wilson, Michael ; Seningen, Justin ; Bhagra, Anjali. / Relapsing fevers and lymphadenopathy in a young woman. In: BMJ Case Reports. 2013.
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