Regulation of histone gene expression

Gary S. Stein, Janet L. Stein, Andre J van Wijnen, Jane B. Lian

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory elements. The three-dimensional organization of the promoter and, in particular, its spatial relationship with the nuclear matrix scaffold, may be important factors of transcription regulation.

Original languageEnglish (US)
Pages (from-to)166-173
Number of pages8
JournalCurrent Opinion in Cell Biology
Volume4
Issue number2
StatePublished - 1992
Externally publishedYes

Fingerprint

Nuclear Matrix
Gene Expression Regulation
Histones
Cell Cycle
S Phase
Genes
Transcription Factors

ASJC Scopus subject areas

  • Cell Biology

Cite this

Stein, G. S., Stein, J. L., van Wijnen, A. J., & Lian, J. B. (1992). Regulation of histone gene expression. Current Opinion in Cell Biology, 4(2), 166-173.

Regulation of histone gene expression. / Stein, Gary S.; Stein, Janet L.; van Wijnen, Andre J; Lian, Jane B.

In: Current Opinion in Cell Biology, Vol. 4, No. 2, 1992, p. 166-173.

Research output: Contribution to journalArticle

Stein, GS, Stein, JL, van Wijnen, AJ & Lian, JB 1992, 'Regulation of histone gene expression', Current Opinion in Cell Biology, vol. 4, no. 2, pp. 166-173.
Stein GS, Stein JL, van Wijnen AJ, Lian JB. Regulation of histone gene expression. Current Opinion in Cell Biology. 1992;4(2):166-173.
Stein, Gary S. ; Stein, Janet L. ; van Wijnen, Andre J ; Lian, Jane B. / Regulation of histone gene expression. In: Current Opinion in Cell Biology. 1992 ; Vol. 4, No. 2. pp. 166-173.
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