Regional Node Dissection for Melanoma: Techniques and Indication

James W. Jakub, Douglas S. Reintgen, Steven Shivers, Solange Pendas

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Because virtually all microscopic nodal disease left untreated in melanoma patients will progress to clinically apparent macroscopic nodal disease, there is worse prognosis with macroscopic nodal disease, and ineffective systemic treatment currently exists, one must be cautious in favoring an observation approach to the regional basin in patients with a positive sentinel lymph node (SLN) in the hopes of avoiding the potential morbidity of a therapeutic node dissection. In the few patients with untreated microscopic nodal disease, the prognosis will be significantly worsened. Until further data are available, melanoma patients with a positive SLN by H&E analysis should proceed to a complete lymph node dissection.

Original languageEnglish (US)
Pages (from-to)247-261
Number of pages15
JournalSurgical Oncology Clinics of North America
Issue number1
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Surgery
  • Oncology


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