Regional myocardial wall thickening response to nitroglycerin. A predictor of myocardial response to aortocoronary bypass surgery

J. H. Chesebro; E. L. Ritman; R. L. Frye; H. C. Smith; B. D. Rutherford; R. E. Fulton; J. R. Pluth; D. A. Barnhorst

doi:10.1161/01.CIR.57.5.952

Regional myocardial wall thickening response to nitroglycerin. A predictor of myocardial response to aortocoronary bypass surgery

J. H. Chesebro, E. L. Ritman, R. L. Frye, H. C. Smith, B. D. Rutherford, R. E. Fulton, J. R. Pluth, D. A. Barnhorst

Physiology & Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The peak rate of systolic wall thickening (p±dT(w)/dt) in regions of the left ventricle (LV) was determined preoperatively by biplane roentgen videometry in 18 patients before and after sublingual administration of nitroglycerin (NTG) and 3-23 months (median 12) after aortocoronary bypass surgery. The regional LV response to NTG was a reliable predictor for postoperative improvement in regional wall dynamics after successful aortocoronary bypass grafting. The ejection fraction response to NTG or surgery will not predict the regional myocardial response to NTG or surgery, nor will the regional response predict the global response. Subendocardial myocardial infarction is another cause of unimproved regional myocardial function after NTG and aortocoronary bypass surgery.

Original language	English (US)
Pages (from-to)	952-957
Number of pages	6
Journal	Unknown Journal
Volume	57
Issue number	5
DOIs	https://doi.org/10.1161/01.CIR.57.5.952
State	Published - 1978

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1161/01.CIR.57.5.952

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title = "Regional myocardial wall thickening response to nitroglycerin. A predictor of myocardial response to aortocoronary bypass surgery",

abstract = "The peak rate of systolic wall thickening (p±dT(w)/dt) in regions of the left ventricle (LV) was determined preoperatively by biplane roentgen videometry in 18 patients before and after sublingual administration of nitroglycerin (NTG) and 3-23 months (median 12) after aortocoronary bypass surgery. The regional LV response to NTG was a reliable predictor for postoperative improvement in regional wall dynamics after successful aortocoronary bypass grafting. The ejection fraction response to NTG or surgery will not predict the regional myocardial response to NTG or surgery, nor will the regional response predict the global response. Subendocardial myocardial infarction is another cause of unimproved regional myocardial function after NTG and aortocoronary bypass surgery.",

author = "Chesebro, {J. H.} and Ritman, {E. L.} and Frye, {R. L.} and Smith, {H. C.} and Rutherford, {B. D.} and Fulton, {R. E.} and Pluth, {J. R.} and Barnhorst, {D. A.}",

year = "1978",

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T1 - Regional myocardial wall thickening response to nitroglycerin. A predictor of myocardial response to aortocoronary bypass surgery

AU - Chesebro, J. H.

AU - Ritman, E. L.

AU - Frye, R. L.

AU - Smith, H. C.

AU - Rutherford, B. D.

AU - Fulton, R. E.

AU - Pluth, J. R.

AU - Barnhorst, D. A.

PY - 1978

Y1 - 1978

N2 - The peak rate of systolic wall thickening (p±dT(w)/dt) in regions of the left ventricle (LV) was determined preoperatively by biplane roentgen videometry in 18 patients before and after sublingual administration of nitroglycerin (NTG) and 3-23 months (median 12) after aortocoronary bypass surgery. The regional LV response to NTG was a reliable predictor for postoperative improvement in regional wall dynamics after successful aortocoronary bypass grafting. The ejection fraction response to NTG or surgery will not predict the regional myocardial response to NTG or surgery, nor will the regional response predict the global response. Subendocardial myocardial infarction is another cause of unimproved regional myocardial function after NTG and aortocoronary bypass surgery.

AB - The peak rate of systolic wall thickening (p±dT(w)/dt) in regions of the left ventricle (LV) was determined preoperatively by biplane roentgen videometry in 18 patients before and after sublingual administration of nitroglycerin (NTG) and 3-23 months (median 12) after aortocoronary bypass surgery. The regional LV response to NTG was a reliable predictor for postoperative improvement in regional wall dynamics after successful aortocoronary bypass grafting. The ejection fraction response to NTG or surgery will not predict the regional myocardial response to NTG or surgery, nor will the regional response predict the global response. Subendocardial myocardial infarction is another cause of unimproved regional myocardial function after NTG and aortocoronary bypass surgery.

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Regional myocardial wall thickening response to nitroglycerin. A predictor of myocardial response to aortocoronary bypass surgery

Abstract

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