Abstract
Regional lung distortion during deflation from total lung capacity to functional residual capacity (FRC) in intact supine and prone anesthetized dogs was determined from the displacement of multiple metallic markers embedded in the lung parenchyma. Distortion was expressed as strain (ε), which is related to fractional length changes. In the supine position, transverse strain (ε(yy)) was larger than vertical strain (ε(xx)) and cephalocaudal strain (ε(zz)) in the upper lobe. The FRC of the lower lobe was smaller than FRC of the upper lobe and all strains were larger, but ε(zz) increased most and became equal to ε(yy). In the prone position, ε(yy) was largest in all upper lobes and in three of four lower lobes. Strains and volumes of the upper and lower lobes were similar. The upper and lower lobes rotated slightly around different axes, indicating that interpleural fissures allow additional degrees of freedom for the lungs to conform to the thoracic cavity. In the prone position, there were no consistent gradients of strain or volume. These results indicate that, in determining the regional distribution of FRC in the recumbent dog, in addition to the effect of gravity on the lung, there are important interactions between lung and thoracic cavity shapes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 164-172 |
| Number of pages | 9 |
| Journal | Journal of Applied Physiology |
| Volume | 58 |
| Issue number | 1 |
| State | Published - 1985 |
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ASJC Scopus subject areas
- Endocrinology
- Physiology
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation
Cite this
Regional lung strain in dogs during deflation from total lung capacity. / Rodarte, J. R.; Hubmayr, R. D.; Stamenovic, D.; Walters, B. J.
In: Journal of Applied Physiology, Vol. 58, No. 1, 1985, p. 164-172.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Regional lung strain in dogs during deflation from total lung capacity
AU - Rodarte, J. R.
AU - Hubmayr, R. D.
AU - Stamenovic, D.
AU - Walters, B. J.
PY - 1985
Y1 - 1985
N2 - Regional lung distortion during deflation from total lung capacity to functional residual capacity (FRC) in intact supine and prone anesthetized dogs was determined from the displacement of multiple metallic markers embedded in the lung parenchyma. Distortion was expressed as strain (ε), which is related to fractional length changes. In the supine position, transverse strain (ε(yy)) was larger than vertical strain (ε(xx)) and cephalocaudal strain (ε(zz)) in the upper lobe. The FRC of the lower lobe was smaller than FRC of the upper lobe and all strains were larger, but ε(zz) increased most and became equal to ε(yy). In the prone position, ε(yy) was largest in all upper lobes and in three of four lower lobes. Strains and volumes of the upper and lower lobes were similar. The upper and lower lobes rotated slightly around different axes, indicating that interpleural fissures allow additional degrees of freedom for the lungs to conform to the thoracic cavity. In the prone position, there were no consistent gradients of strain or volume. These results indicate that, in determining the regional distribution of FRC in the recumbent dog, in addition to the effect of gravity on the lung, there are important interactions between lung and thoracic cavity shapes.
AB - Regional lung distortion during deflation from total lung capacity to functional residual capacity (FRC) in intact supine and prone anesthetized dogs was determined from the displacement of multiple metallic markers embedded in the lung parenchyma. Distortion was expressed as strain (ε), which is related to fractional length changes. In the supine position, transverse strain (ε(yy)) was larger than vertical strain (ε(xx)) and cephalocaudal strain (ε(zz)) in the upper lobe. The FRC of the lower lobe was smaller than FRC of the upper lobe and all strains were larger, but ε(zz) increased most and became equal to ε(yy). In the prone position, ε(yy) was largest in all upper lobes and in three of four lower lobes. Strains and volumes of the upper and lower lobes were similar. The upper and lower lobes rotated slightly around different axes, indicating that interpleural fissures allow additional degrees of freedom for the lungs to conform to the thoracic cavity. In the prone position, there were no consistent gradients of strain or volume. These results indicate that, in determining the regional distribution of FRC in the recumbent dog, in addition to the effect of gravity on the lung, there are important interactions between lung and thoracic cavity shapes.
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M3 - Article
C2 - 3968007
AN - SCOPUS:0021860979
VL - 58
SP - 164
EP - 172
JO - Journal of Applied Physiology
JF - Journal of Applied Physiology
SN - 8750-7587
IS - 1
ER -