Regional differences in oesophageal motor function

J. L. Wise, Joseph A Murray, J. L. Conklin

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We tested the hypotheses that oesophageal bolus transit and motor function vary regionally, with bolus viscosity and with body position. In healthy volunteers, we measured the bolus head advance time, bolus presence time and bolus transit time in the proximal and distal oesophagus using water and viscous materials. We compared concurrent manometric responses. Bolus head advance time, bolus presence time and bolus transit time were longer in the distal oesophagus during water and viscous swallows in the upright and supine positions. The total bolus head advance time and transit time, measured across the entire oesophageal body, were shorter for water than viscous swallows. The amplitudes of peristaltic pressure waves were lower for viscous swallows, and varied as a function of region. These studies demonstrated true functional differences between the proximal and distal oesophagus using multichannel intraluminal impedance and that the viscosity of the bolus is a determinant of oesophageal function.

Original languageEnglish (US)
Pages (from-to)31-37
Number of pages7
JournalNeurogastroenterology and Motility
Volume16
Issue number1
DOIs
StatePublished - Feb 2004

Fingerprint

Swallows
Esophagus
Head
Viscosity
Water
Supine Position
Electric Impedance
Healthy Volunteers
Pressure

Keywords

  • Deglutition
  • Motility
  • Oesophagus
  • Peristalsis
  • Swallowing

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology
  • Neuroscience(all)

Cite this

Regional differences in oesophageal motor function. / Wise, J. L.; Murray, Joseph A; Conklin, J. L.

In: Neurogastroenterology and Motility, Vol. 16, No. 1, 02.2004, p. 31-37.

Research output: Contribution to journalArticle

Wise, J. L. ; Murray, Joseph A ; Conklin, J. L. / Regional differences in oesophageal motor function. In: Neurogastroenterology and Motility. 2004 ; Vol. 16, No. 1. pp. 31-37.
@article{e1b25da753b643d3928e8dbff1ed297c,
title = "Regional differences in oesophageal motor function",
abstract = "We tested the hypotheses that oesophageal bolus transit and motor function vary regionally, with bolus viscosity and with body position. In healthy volunteers, we measured the bolus head advance time, bolus presence time and bolus transit time in the proximal and distal oesophagus using water and viscous materials. We compared concurrent manometric responses. Bolus head advance time, bolus presence time and bolus transit time were longer in the distal oesophagus during water and viscous swallows in the upright and supine positions. The total bolus head advance time and transit time, measured across the entire oesophageal body, were shorter for water than viscous swallows. The amplitudes of peristaltic pressure waves were lower for viscous swallows, and varied as a function of region. These studies demonstrated true functional differences between the proximal and distal oesophagus using multichannel intraluminal impedance and that the viscosity of the bolus is a determinant of oesophageal function.",
keywords = "Deglutition, Motility, Oesophagus, Peristalsis, Swallowing",
author = "Wise, {J. L.} and Murray, {Joseph A} and Conklin, {J. L.}",
year = "2004",
month = "2",
doi = "10.1046/j.1365-2982.2003.00455.x",
language = "English (US)",
volume = "16",
pages = "31--37",
journal = "Neurogastroenterology and Motility",
issn = "1350-1925",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Regional differences in oesophageal motor function

AU - Wise, J. L.

AU - Murray, Joseph A

AU - Conklin, J. L.

PY - 2004/2

Y1 - 2004/2

N2 - We tested the hypotheses that oesophageal bolus transit and motor function vary regionally, with bolus viscosity and with body position. In healthy volunteers, we measured the bolus head advance time, bolus presence time and bolus transit time in the proximal and distal oesophagus using water and viscous materials. We compared concurrent manometric responses. Bolus head advance time, bolus presence time and bolus transit time were longer in the distal oesophagus during water and viscous swallows in the upright and supine positions. The total bolus head advance time and transit time, measured across the entire oesophageal body, were shorter for water than viscous swallows. The amplitudes of peristaltic pressure waves were lower for viscous swallows, and varied as a function of region. These studies demonstrated true functional differences between the proximal and distal oesophagus using multichannel intraluminal impedance and that the viscosity of the bolus is a determinant of oesophageal function.

AB - We tested the hypotheses that oesophageal bolus transit and motor function vary regionally, with bolus viscosity and with body position. In healthy volunteers, we measured the bolus head advance time, bolus presence time and bolus transit time in the proximal and distal oesophagus using water and viscous materials. We compared concurrent manometric responses. Bolus head advance time, bolus presence time and bolus transit time were longer in the distal oesophagus during water and viscous swallows in the upright and supine positions. The total bolus head advance time and transit time, measured across the entire oesophageal body, were shorter for water than viscous swallows. The amplitudes of peristaltic pressure waves were lower for viscous swallows, and varied as a function of region. These studies demonstrated true functional differences between the proximal and distal oesophagus using multichannel intraluminal impedance and that the viscosity of the bolus is a determinant of oesophageal function.

KW - Deglutition

KW - Motility

KW - Oesophagus

KW - Peristalsis

KW - Swallowing

UR - http://www.scopus.com/inward/record.url?scp=1342331495&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1342331495&partnerID=8YFLogxK

U2 - 10.1046/j.1365-2982.2003.00455.x

DO - 10.1046/j.1365-2982.2003.00455.x

M3 - Article

C2 - 14764203

AN - SCOPUS:1342331495

VL - 16

SP - 31

EP - 37

JO - Neurogastroenterology and Motility

JF - Neurogastroenterology and Motility

SN - 1350-1925

IS - 1

ER -